research Hair Follicle Sulfotransferase Activity and Effectiveness of Oral Minoxidil in Androgenetic Alopecia
Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.
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510-540 / 1000+ results research Dermatologic Changes in Experimental Model of Long COVID
Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
research Long-Acting Microneedle Formulations
Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
research An ERK-Dependent Molecular Switch Antagonizes Fibrosis and Promotes Regeneration in Spiny Mice
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
research Somatotropin Penetration Testing From Topical Formulations Applied to the Skin
The new topical growth hormone formula has high skin penetration and bioavailability.
research The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome: A Review
Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.
research Summary of the Preceding Three Alopecia Areata Research Summits: What’s Past Is Prologue
New treatments and strategies are needed for Alopecia Areata, focusing on immune response and better trial designs.
research The Impact of Hair Loss in Cambodia: Causes, Prevention Methods, and Treatment Solutions
A combined approach of medical treatments, natural remedies, diet, and stress management is best for hair regrowth in Cambodia.
research Application of Multi-Omics Techniques to Androgenetic Alopecia: Current Status and Perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Metabolomics Reveals Metabolites Associated with Hair Follicle Cycle in Cashmere Goats
Metabolites and diet affect hair growth cycles in cashmere goats.
research The Vitamin B5/Coenzyme A Axis: A Target for Immunomodulation?
Vitamin B5 and coenzyme A may help regulate the immune system and could improve treatments for chronic diseases and cancer.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Melanocytes in Regenerative Medicine Applications and Disease Modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research Natural Bioactive Compounds as Potential Sources for Alleviation and Treatment of Androgenetic Alopecia: A Research Advance
Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.
research A Guide to the Use of Bioassays in Exploration of Natural Resources
Bioassays help find useful compounds in nature for making medicines, supplements, and cosmetics.
research Apoptotic Dysregulation Mediates Stem Cell Competition and Tissue Regeneration
Cells lacking the Bax protein can outcompete others, leading to better tissue repair and hair growth.
research Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions
One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Male Androgenetic Alopecia
New understanding of hair loss could lead to better treatments.
research 1,314
The convention highlighted the importance of comprehensive patient care and early diagnosis in dermatology.
research Unveiling the Potential of Sansevieria Trifasciata Prain Fraction for the Treatment of Androgenetic Alopecia by Inhibiting Androgen Receptors Based on LC-MS/MS Analysis and In-Silico Studies
Sansevieria trifasciata Prain shows promise for treating hair loss by inhibiting androgen receptors.
research Nitric Oxide Signal Transduction and Its Role in Skin Sensitization
Nitric oxide is important for skin functions and both helps protect against and contributes to skin inflammation and sensitization.
research Clinical Development of Topoisomerase-Interactive Drugs
New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
research Androgen Receptor in Human Health: A Potential Therapeutic Target
The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.
research Disturbed Keratinocyte Differentiation in Transgenic Mice and Organotypic Keratinocyte Cultures Due to Spermidine/Spermine N1-Acetyltransferase Overexpression
In this study, overexpression of spermidine/spermine N1-acetyltransferase (SSAT) in transgenic mice led to increased putrescine levels, causing permanent hair loss and skin abnormalities such as dermal cysts and epidermal utriculi due to disturbed keratinocyte differentiation. This was characterized by altered expression of cytokeratins and filaggrin. The study found that reducing putrescine levels with DFMO treatment could alleviate these skin changes and promote hair regrowth, highlighting the importance of proper polyamine metabolism regulation for normal keratinocyte differentiation and hair follicle function. These findings had potential implications for understanding skin disorders and hair growth.
research Cutaneous Retinoic Acid Levels Determine Hair Follicle Development And Downgrowth
The right amount of retinoic acid is essential for normal hair growth and development.
research From Eye Care to Hair Growth: Bimatoprost
Bimatoprost helps with hair growth and eye conditions but can be costly and have side effects.
research Steroid 5α-Reductase Inhibitors
New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.
research Can Plant-Derived Phytochemicals Provide Symptom Relief for Hair Loss? A Critical Review
Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
research Footprints of the EADV: A Meeting Report from the 17th Congress of the European Academy of Dermatology and Venereology
The conference highlighted new dermatological treatments and emphasized early intervention and addressing conditions lacking evidence-based treatments.