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This study found that skin-derived precursor cells in mice can originate from both neural crest and somite lineages but show functional similarities regardless of their developmental origins.

This paper reviews the role of the telomere-telomerase system in cellular ageing and cancer, discussing potential therapies but reporting no new experimental results.

This study found that large excisional wounds in rats across seven strains do not regenerate new hair follicles, unlike in mice, possibly due to differences in epidermal competence and transcriptional profiles.

In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.

In this study, a mixture of tocopherol acetate, L-menthol, and stevioside was more effective in promoting hair growth in mice compared to tocopherol acetate or L-menthol alone.

This study found that tdDPC-EVs significantly improved wound healing by enhancing angiogenesis through the KLF4/VEGFA axis, offering advantages over traditional DPC-EVs.

This review synthesizes current advances in transcriptomics and RNA regulatory networks, alongside stem cell-derived skin organoid research, to propose a conceptual framework for understanding and potentially guiding regenerative skin repair, without claiming clinical readiness.

In this study, researchers used transcriptomics and modeling to uncover previously unknown cell populations and marker genes in developing hair follicles, providing insights into early cell fate establishment and offering tools for further research on skin appendages.

This study found that miR-432 inhibits KRT83 expression, revealing potential molecular mechanisms for the formation of curly fleece in Tan sheep and suggesting implications for understanding curly hair formation in humans.

This article outlines methods to study the skin and its molecular traits, focusing on interpretation and techniques applicable to mouse models, including diverse assays and approaches like electron microscopy and large-scale lipid analyses.

This study analyzed gene expression in Pashmina goats and identified key biological processes and molecular functions involved in long-fibre production, suggesting potential pathways for enhancing this trait in other goat breeds.

Innovative methods are reducing animal testing and improving biomedical research.

This study identified core genes and pathways involved in androgenetic alopecia, finding that genes related to hair follicle development are down-regulated, while those linked to immune responses are up-regulated, highlighting potential therapeutic targets.

This study found that ingenol mebutate treatment led to gene expression changes in actinic keratoses, with complete lesion clearance in 40% of patients and identified genetic markers potentially predicting treatment response.

This study identified a proliferative intermediate transcriptional state associated with the transition from secondary hair germ cells to lower hair follicle-associated cells during early hair follicle regeneration in mice.

This study found thousands of differentially expressed genes and proteins that may be associated with wool growth, suggesting potential gene families involved in hair growth regulation.

This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.

This study suggests that infiltrating M2 macrophages promote wound-induced hair neogenesis in mice by producing growth factors that activate the wnt signaling pathway during the late phase of wound healing.

This study found that a novel 3D in vitro culture condition improved stemness markers and proliferation potential in human dermal stem/progenitor cells compared to traditional 2D methods.

This study found that transfecting hair follicle stem cells with a PEI-DNA complex expressing hTERT stimulated hair growth in rats by inducing follicle neogenesis and promoting the anagen phase.

This study identified key genes and miRNAs involved in feather morphogenesis in Zhedong White geese, highlighting a negative correlation between FOXO3 and miR-144-y.

This study identified 53 keratins in the yak genome, predicting diverse phosphorylation sites and subcellular localizations, and highlighted strong gene expression correlations during the yak hair follicle development cycle.

Using high-throughput proteomics, this study identified 34 differentially expressed proteins in the lesional skin of adults with scalp psoriasis, suggesting a cytokine storm response linked to bacterial antigens.

This study highlights that a novel radially aligned nanofiber scaffold with dual growth factor gradients significantly enhances wound healing, promoting cell migration, epidermal regeneration, and angiogenesis, ultimately leading to improved wound closure, immune regulation, and tissue remodeling compared to other groups.

In this study, AMACO was found to be non-essential for the formation or function of anchoring cords in mice, despite its presence in the structure.

This study reports a new optimized protocol for isolating and labeling single cells from neonatal mouse skin, enabling high-quality single cell RNA sequencing for lineage-specific cell analysis.

In this study, researchers found that specific mutations in iRhom2 in mice lead to skin and hair abnormalities which depend on the presence of the protein ADAM17, suggesting a complex role for iRhom2 in tissue development and potential implications for treating tylosis with oesophageal cancer.

This study suggests that hemoglobin α expression in the epidermis is induced by oxidative stress and may function as an antioxidant, contributing to skin barrier function.

This study generated a transcriptomic map of human hair follicle compartments, providing a database for identifying compartment-specific gene expression which may aid in developing targeted treatments for hair follicle disorders.

This study found that short-term treatment with ROCKi significantly increased keratinocyte stem cell proliferation without affecting their stemness, suggesting a potential safe approach for improving in vitro keratinocyte cultures for clinical applications.