Keratinocytes of the Upper Epidermis and Isthmus of Hair Follicles Express Hemoglobin mRNA and Protein
November 2023
in “
The journal of investigative dermatology/Journal of investigative dermatology
”
keratinocytes upper epidermis isthmus of hair follicles hemoglobin mRNA hemoglobin protein Hemoglobin Alpha HBA oxidative stress UV irradiation human epidermal keratinocytes skin barrier function immunofluorescence staining RNA isolation RT-qPCR analysis microarray analysis single-cell RNA-sequencing analysis RNA interference cellular ROS staining skin cells hair follicle region hemoglobin UV light exposure skin protection fluorescent staining RNA extraction quantitative PCR gene expression analysis single-cell RNA sequencing gene silencing reactive oxygen species staining
Studysummary This study suggests that hemoglobin α expression in the epidermis is induced by oxidative stress and may function as an antioxidant, contributing to skin barrier function.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
