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GlossaryImmunostaining (Immunofluorescence Staining)

technique using antibodies to detect specific proteins in tissues

Immunofluorescence (IF) is a laboratory technique used to visualize the presence and location of specific proteins or antigens in cells or tissue sections by using antibodies that are chemically linked to a fluorescent dye. When these antibodies bind to their target, the fluorescent dye can be seen under a microscope with the appropriate light, allowing researchers to study the distribution and abundance of the proteins of interest.

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research Position Effect on FGF13 Associated with X-Linked Congenital Generalized Hypertrichosis

44 citations, April 2013 in “Proceedings of the National Academy of Sciences of the United States of America”

FGF13 gene changes cause excessive hair growth in a rare condition.

research Upregulation of Interfollicular Epidermal and Hair Infundibulum β-Catenin Expression in Gsdma3 Mutant Mice

11 citations, June 2012 in “Acta histochemica”

Mice with a Gsdma3 gene mutation have thicker skin and longer hair follicle openings due to increased β-catenin levels.

Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes

research Analysis of the Expression Pattern of the Carrier Protein Transthyretin and Its Receptor Megalin in the Human Scalp Skin and Hair Follicles: Hair Cycle-Associated Changes

6 citations, November 2010 in “Histochemistry and cell biology”

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

research EGFR Marks a Subpopulation of Dermal Mesenchymal Cells Highly Expressing IGF1 Which Enhances Hair Follicle Regeneration

1 citations, May 2023 in “PubMed”

A certain type of skin cell, marked by EGFR, produces a lot of IGF1 and helps hair follicles grow back faster.

research Regeneration of Mouse Skin Melanocyte Stem Cells In Vivo and In Vitro

1 citations, January 2018 in “Methods in molecular biology”

The research found ways to activate melanocyte stem cells for potential treatment of skin depigmentation conditions.

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