Analysis Of The Function Of ADAM17 In IRhom2 Curly-Bare And Tylosis With Esophageal Cancer Mutant Mice

    June 2023 in “ Journal of cell science ”
    Ariana Rabinowitsch, Thorsten Maretzky, Gisela Weskamp … Carl P. Blobel
    Studysummary In this study, researchers found that specific mutations in iRhom2 in mice lead to skin and hair abnormalities which depend on the presence of the protein ADAM17, suggesting a complex role for iRhom2 in tissue development and potential implications for treating tylosis with oesophageal cancer.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on journals.biologists.com →
    Discuss this study in the Community →

    Research cited in this study 1

    1. Curly Bare (Cub), a New Mouse Mutation on Chromosome 11 Causing Skin and Hair Abnormalities, and a Modifier Gene (Mcub) on Chromosome 5 Genomics · 2003