124 citations,
July 2017 in “eLife” Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
61 citations,
October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
53 citations,
January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.
36 citations,
March 2014 in “Molecular and Cellular Biology” Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.
30 citations,
December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
9 citations,
November 2022 in “Applied sciences” Marine algae compounds may improve skin health and promote hair growth.
9 citations,
July 2020 in “Biomedicine & Pharmacotherapy” Mitochondrial therapy and platelet-rich plasma therapy both stimulated hair regrowth in aging mice, with mitochondrial therapy showing similar effectiveness to plasma therapy.
8 citations,
July 2022 in “International Journal of Molecular Sciences” Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
7 citations,
February 2015 in “Journal of comparative pathology” CD8+ T cells play a key role in graft-versus-host disease in certain mice models.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
3 citations,
March 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Zebrafish are useful for studying and developing treatments for human skin diseases.
2 citations,
May 2023 in “International Journal of Molecular Sciences” The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
2 citations,
March 2019 in “Veterinary dermatology” Thymoma in cats can cause hair loss without inflammation.
1 citations,
January 2023 in “Science Advances” The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.
1 citations,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
January 2025 in “AAPS PharmSciTech” Transethosomes improve drug delivery through the skin and show promise for treating various conditions.
August 2024 in “Indian Journal of Skin Allergy” Stem-cell therapy shows promise for skin conditions but needs more research.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells and certain hair follicle areas produce hemoglobin, which may help protect against oxidative stress like UV damage.
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
67 citations,
June 2019 in “Proceedings of the National Academy of Sciences” A new 3D culture system helps grow and study mouse skin stem cells for a long time.
2 citations,
April 2017 in “Actas Dermo-Sifiliográficas” Best treatment for Frontal Fibrosing Alopecia is 5-alpha-reductase inhibitors and intralesional corticosteroids.
31 citations,
July 2012 in “Journal of Lipid Research” ACBP is crucial for healthy skin in mice.
21 citations,
March 2018 in “American Journal Of Pathology” Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
4 citations,
July 2022 in “Annals of translational medicine” Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
1 citations,
October 2022 in “Bioengineering” Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.
October 2024 in “Acta Biomaterialia” Collagen makes skin stiff, and preservation methods greatly increase tissue stiffness.
99 citations,
May 1998 in “Journal of biological chemistry/The Journal of biological chemistry” Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.
63 citations,
April 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
61 citations,
January 2011 in “PloS one” Notch signaling is essential for healthy skin and hair follicle maintenance.
November 2023 in “IntechOpen eBooks” Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.