Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin Hydrogels
October 2022
in “
Bioengineering
”
TLDR Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.
The study "Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin Hydrogels" found that adding keratin to a collagen hydrogel significantly increased the differentiation of keratinocytes, the primary cells in the skin's outer layer. This was indicated by increased lysosomal activity and the expression of involucrin, a differentiation marker. The addition of calcium further enhanced this differentiation. The study suggests that keratin plays a crucial role in promoting keratinocyte differentiation, which could have implications for skin health and hair growth. The study involved multiple experiments, each with a sample size of 4 or 60.
