Exploring the Interplay Between Arsenic and Cutaneous Physiology, Pathology, and Regeneration
November 2023
in “
IntechOpen eBooks
”
Studysummary This source highlights that arsenic exposure through contaminated groundwater is a significant global health risk, leading to skin and hair conditions such as pigmentation changes, skin irritation, alopecia, and can eventually result in skin cancer.
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The document "Exploring the Interplay between Arsenic and Cutaneous Physiology, Pathology, and Regeneration" discusses the significant health hazards posed by arsenic exposure, particularly through contaminated drinking water. Chronic exposure leads to various skin conditions, including hyperpigmentation, keratosis, and skin cancers like basal cell carcinoma and Bowen’s disease. The document highlights the biochemical processing of arsenic in the liver, its systemic effects such as oxidative stress and DNA damage, and the need for reliable biomarkers to assess exposure. It underscores the importance of effective management strategies, such as avoiding contaminated water and using alternative sources, to mitigate arsenic toxicity.