July 2026 in “Frontiers in Bioengineering and Biotechnology” This review highlights the development and assessment of human-relevant models for cutaneous wound healing, emphasizing that a combination of systems, such as organoid platforms and skin-on-a-chip systems, is necessary to overcome limitations of traditional methodologies and address chronic wound challenges.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study evaluated the development of a herbal anti-dandruff shampoo using natural ingredients like fenugreek, curry leaves, and neem, finding it effective in reducing dandruff and nourishing the scalp without causing irritation, and suggesting it as a safe and economical alternative to synthetic shampoos.
October 2023 in “Research Review” This source describes the development, structure, and types of skin appendage tumors, noting both benign and malignant forms, potential associations with syndromes, and categories based on follicular differentiation.
April 2023 in “Journal of Investigative Dermatology” This report details the development of a PSR™ Terminalia extract with antioxidant and anti-aging potential, highlighting its rich composition in phenolic acids, polysaccharides, and organic acids, without new clinical results.
April 2023 in “Journal of Investigative Dermatology” This study found that using 3D total body imaging with convolution neural networks accurately identifies risk phenotypes for melanoma, suggesting improved objective stratification for early detection and prevention.
September 2022 in “Research Square (Research Square)” In this study, the DIET-AI model, developed from a large dataset of over 200,000 images, demonstrated diagnostic performance for 31 skin diseases comparable to dermatologists of varying experience levels in 15 hospitals across China, supporting its potential effectiveness in clinical settings.
July 2022 in “International Journal of Science and Research (IJSR)” This study describes the development of an herbal hair oil using thirteen ingredients to address various hair problems like baldness, dandruff, and hair damage, although the abstract does not report results or evaluate efficacy.
August 2018 in “Journal of Investigative Dermatology” This study found that humans have a much higher eccrine gland density than chimpanzees and macaques, suggesting a unique evolutionary path for human skin features.
January 1997 in “Elsevier eBooks” This review discusses the development and types of hair and nails as skin appendages and reports no new research findings.
218 citations
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May 2014 in “Experimental Dermatology” This review explores the evolution and development of skin-associated adipose tissue and proposes new nomenclature for the cells and adipose tissue underlying the reticular dermis, without reporting clinical results.
2 citations
,
January 2006 in “Technical report” This chapter reviews the development of skin-specific outcome instruments for autoimmune diseases like cutaneous lupus erythematosus and dermatomyositis, highlighting a need for a broader community-involved process across other diseases but reports no new results.
84 citations
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April 2013 in “Applied Microbiology and Biotechnology” This review discusses the current research and development of mannosylerythritol lipids, particularly focusing on their potential commercial applications in cosmetics; it reports no new results.
50 citations
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November 1984 in “Journal of Heredity” This study found that supplementing zinc improved certain developmental defects in mice with the lethal-milk mutation, although it did not increase the survival rate among backcross progeny.
39 citations
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February 2024 in “Small” This review discusses the evolution and development of smart and multifunctional microneedles, highlighting their potential future importance in medical applications, but it reports no new experimental results.
38 citations
,
July 2004 in “Journal of experimental zoology. Part B, Molecular and developmental evolution” This article discusses a hypothesis on the development and evolution of scales, hairs, and feathers from fish to amniotes, based on regions of dermo-epidermal interactions in skin, but reports no new findings.
28 citations
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November 2020 in “Polymers” This study found that crosslinking buffalo gelatin with different methods can modify its properties and potential as a skin substitute, though double-crosslinking may increase immunogenicity slightly.
24 citations
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July 2021 in “Pharmaceutics” This article reviews the JAK signaling pathway and the development of ruxolitinib cream as a targeted treatment for inflammatory skin diseases, reporting no new clinical results.
5 citations
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September 2018 in “Journal of Investigative Dermatology” Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.
4 citations
,
January 1987 in “Annual reports in medicinal chemistry” This review discusses recent developments in dermatological treatments for skin conditions such as acne, psoriasis, acute inflammation, and alopecia but reports no new clinical results.
2 citations
,
July 2025 in “Analytical Chemistry” This study reported the development of a workflow that combines SIMS and X-ray elemental mapping techniques for multimodal imaging at the single cell level, successfully applied to visualize elements, metals, and lipids in porcine skin without loss or delocalization.
January 2025 in “Lusophone University Repository” This study investigated the presence and development of anti-aging cosmetics using metallic nanoparticles in the market, finding significant knowledge gaps and safety concerns that have led to recent EU regulations set to restrict their use until conclusive safety studies are presented.
January 2024 in “Research Portal Denmark” This study reports the development of an artificial skin membrane incorporating hair follicles, intended as an in vitro model to better estimate drug permeation with less variability than current models used in transdermal drug delivery research.
December 2017 in “British Journal of Dermatology” Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.
131 citations
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March 2004 in “The American journal of pathology” This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.
46 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that Acvr1b signaling is crucial for both hair follicle development and cycling in mice, with the genetic disruption leading to hair loss and a thickened epidermis.
14 citations
,
June 2022 in “BMC genomics” This study identified key genes involved in hair follicle development in Merino sheep, offering insights for improving wool production and providing a basis for future breeding programs.
5 citations
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April 2024 in “Biology” This review explores the current understanding of hair follicle development and regeneration, emphasizing the molecular pathways involved and the potential for bioengineering hair follicles in vitro to advance hair regeneration strategies.
January 2006 in “Advances in developmental biology” This review discusses the roles of the hairless (HR) protein as a corepressor, particularly its impact on RORα-mediated transcriptional repression, and reports no new experimental findings.
99 citations
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February 2000 in “PubMed” This study found that overexpression of PKCepsilon in transgenic mice reduced papilloma development but accelerated carcinoma formation in a skin tumor promotion model.
118 citations
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January 2004 in “European Journal of Cell Biology” Balanced protease activity is crucial for healthy skin and hair development.