TLDR Certain genetic markers linked to wool quality in Rambouillet sheep were identified, which can guide better breeding choices.
The study on Rambouillet sheep identified significant genetic markers associated with wool quality traits, involving 313 ram lambs over three years. Key findings include SNPs on chromosomes 1, 2, 4, 15, and 19, explaining 6.13% to 8.25% of phenotypic variance. Notable markers include rs404487383 and rs406184307 on chromosome 1 for fiber diameter, and rs420943224 for clean fleece weight. Genes like ABCC8 and ULK4 were linked to skin wrinkle and face wool scores, respectively. These results suggest potential for genetic improvement in wool quality through marker-assisted selection, although further research is needed due to small sample sizes in some genotype categories.
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April 2021 in “IntechOpen eBooks” The PCR technique can identify genetic differences in a wool-related gene among different sheep breeds, which may help improve wool and pelt quality.
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May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
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August 2015 in “Journal of Animal Science” The MTR gene affects wool quality and production in Chinese Merino sheep.
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July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
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March 2023 in “Scientific Reports” Researchers developed a new method to test hair growth drugs and found that adult cells are best for hair growth, but the method needs improvement as it didn't create mature hair follicles.
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June 2016 in “Yāftah/hā-yi nuvīn dar ̒ulūm-i zīstī” Sheep testis extract significantly improves wound healing and hair growth in rats.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.