TLDR The PCR technique can identify genetic differences in a wool-related gene among different sheep breeds, which may help improve wool and pelt quality.
The review explores the use of PCR to detect polymorphisms in the KRTAP1.1 gene among Romney, Merino, and Swakara sheep breeds. It identifies three length variation alleles (A, B, and C) of the KRTAP1.1 gene, which are 341, 311, and 281 base pairs long, respectively. These genetic variations, caused by a 30 bp insertion/deletion, could influence wool quality. The findings suggest that further research and new typing methods are needed to understand the genetic diversity in wool-related genes and potentially improve wool and pelt quality traits.
98 citations,
May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
117 citations,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
10 citations,
November 2021 in “International journal of molecular sciences” Sheep and goat hair fibers are complex due to keratin-associated proteins, which are important for fiber properties and growth.
June 2024 in “Computational and Structural Biotechnology Journal” Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
Wild African goats have genetic adaptations for surviving harsh desert conditions.
3 citations,
August 2022 in “Archives animal breeding/Archiv für Tierzucht” Certain genetic changes in the KAP22-1 gene are linked to better wool quality in Egyptian sheep.
1 citations,
September 2023 in “Animals” A new goat gene affects cashmere fiber thickness; certain variations can make the fibers coarser.
