Application of PCR Technique to Detect Polymorphism of the KRTAP1.1 Gene in Three Sheep Breeds: A Review

    September 2021 in “ IntechOpen eBooks ”
    Theopoline Omagano Itenge
    TLDR The PCR technique can identify genetic differences in a wool-related gene among different sheep breeds, which may help improve wool and pelt quality.
    The review explores the use of PCR to detect polymorphisms in the KRTAP1.1 gene among Romney, Merino, and Swakara sheep breeds. It identifies three length variation alleles (A, B, and C) of the KRTAP1.1 gene, which are 341, 311, and 281 base pairs long, respectively. These genetic variations, caused by a 30 bp insertion/deletion, could influence wool quality. The findings suggest that further research and new typing methods are needed to understand the genetic diversity in wool-related genes and potentially improve wool and pelt quality traits.
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