Comparative Histomorphometric and Transcriptomic Analysis Reveals Potential Genetic Determinants of Pelage Variation Between Hairy and Coarse-Woolly Sheep

November 2025 in “ BMC Genomics ”

Qing Liang, Dejun Ji, Xianwei Wang, Xu Peng, Jingxin Zhang, Chenjuan Ge, Yulu Zheng, Tengyun Gao, Yinghua Shi, Zejun Xu, Tong Fu, Sen Ma

KAP20-2 KRT6A EDA2R lipid metabolism subcutaneous adiposity immunoregulation

Studysummary This study identified genetic differences between Australian White Sheep and Hu Sheep that may explain their distinct pelage types, with a focus on subcutaneous adiposity and immunoregulation. The findings suggest potential targets for breeding climate-resilient sheep, enhancing our understanding of heat tolerance in these breeds.

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