Identification of the Ovine Keratin-Associated Protein 21-1 Gene and Its Association with Variation in Wool Traits

    July 2019 in “ Animals ”
    Shaobin Li, Huitong Zhou, Hua Gong, Fangfang Zhao, Jiqing Wang, Xiu Liu, Jiang Hu, Yuzhu Luo, Jonathan G. H. Hickford
    TLDR The KRTAP21-1 gene affects wool yield and can help improve wool production.
    The study identified the ovine keratin-associated protein 21-1 gene (KRTAP21-1) and its variants in 360 Merino × Southdown-cross lambs, finding that the AA genotype was associated with higher wool yield compared to the AC genotype. This gene, located on sheep chromosome 1 and similar to the human KRTAP21-1 gene, was expressed in sheep skin and suggested as a genetic marker for improving wool production by affecting yield without significantly altering greasy fleece weight.
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