Sequence Variation in Caprine KRTAP6-2 Affects Cashmere Fiber Diameter

August 2022 in “ Animals ”

Jian Cao, Jiqing Wang, Huitong Zhou, Jiang Hu, Xiu Liu, Shaobin Li, Yuzhu Luo, Jonathan G. H. Hickford

KRTAP6-2 single nucleotide polymorphisms SNPs fiber diameter molecular marker gene variation genetic marker

Studysummary In this study, a specific genetic variant of KRTAP6-2 in Longdong cashmere goats was associated with finer cashmere fiber diameter, suggesting its potential as a molecular marker for breeding improvements.

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research The Complexity of the Ovine and Caprine Keratin-Associated Protein Genes

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This review discusses the role of keratin-associated proteins in the growth and characteristics of wool and hair fibres from sheep and goats, and highlights areas for future research, but it presents no new findings.

research Characterization of an Ovine Keratin Associated Protein Gene, Producing a Protein Rich in Glycine and Tyrosine, Lacking in Cysteine

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In this study, the identification of a novel KAP gene in sheep, named KRTAP36-1, was associated with increased prickle factor in wool, suggesting its potential as a genetic marker for breeding purposes.

research Variation in the Caprine Keratin-Associated Protein 15-1 (KAP15-1) Gene Affects Cashmere Fibre Diameter

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In this study, variation in the KRTAP15-1 gene in goats was linked to changes in cashmere fibre diameter, with specific variants showing dominant or recessive effects.

research Wool Keratin-Associated Protein Genes in Sheep: A Review

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This review explains the genetic diversity of sheep wool keratin-associated protein genes and explores how this variation might be leveraged for selective breeding to enhance wool fiber traits.

research The Sheep KAP8-2 Gene, A New KAP8 Family Member That Is Absent In Humans

25 citations , September 2014 in “SpringerPlus”

This study found that sheep possess a polymorphic KAP8-2 gene that shares high sequence identity with the KAP8-2 gene in goats and reindeer.

research An Updated Nomenclature for Keratin-Associated Proteins

92 citations , January 2012 in “International Journal of Biological Sciences”

This article proposes an updated naming system for keratin-associated proteins and genes, aiming to improve data storage and retrieval by including species information and genetic variation.

research Effect of the Polymorphisms of Keratin Associated Protein 8.2 Gene on Fiber Traits in Inner Mongolia Cashmere Goats

20 citations , May 2007 in “Asian-Australasian Journal of Animal Sciences”

This study found that polymorphisms in the KAP8.2 gene in Chinese Inner Mongolia cashmere goats are associated with variations in cashmere fibre diameter, suggesting its potential as a molecular marker for this trait.

research Human KAP Genes: Only Half of It? Extensive Size Polymorphisms in Hair Keratin-Associated Protein Genes

53 citations , June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

This article reviews extensive genetic polymorphisms in the keratin-associated proteins of human hair, indicating complexity but reporting no new clinical results and calls for further research on their potential impact on hair structure.

research The Role of Keratin Proteins and Their Genes in the Growth, Structure, and Properties of Hair

228 citations , January 1997 in “Birkhäuser Basel eBooks”

This article integrates existing literature on hair follicle structure and formation at the cellular and molecular level, reporting no new findings.