TLDR Genetic variation in the KRTAP15-1 gene affects wool yield in sheep.
The study investigated the genetic variation in the ovine keratin-associated protein 15-1 gene (KRTAP15-1) and its effect on wool traits in 396 Merino × Southdown-cross sheep. Four variants (A to D) were identified, with three being non-synonymous. Variant B was associated with decreased wool yield, while variant C was linked to increased wool yield and decreased fibre diameter standard deviation. Sheep with genotype AC had a higher wool yield compared to those with genotypes AA or AB.
29 citations,
September 2017 in “Genes” Selecting specific KRTAP26-1 gene variants can improve wool quality in sheep.
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42 citations,
January 2017 in “Genes” The gene KAP22-1 affects wool yield and fiber shape in sheep.
98 citations,
May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
53 citations,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” KAP genes show significant genetic variability, but its impact on hair traits is unclear.
100 citations,
December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
191 citations,
November 1959 in “Annals of the New York Academy of Sciences” Hair and wool have complex microscopic structures with microfibrils and varying cystine content.
