TLDR Selecting specific KRTAP26-1 gene variants can improve wool quality in sheep.
The study identified the ovine Keratin-Associated Protein 26-1 (KRTAP26-1) gene and its variants in 383 Merino-Southdown cross sheep, revealing four variants (A-D). Variant B was associated with increased mean fiber diameter (MFD), mean fiber curvature, and prickle factor, while variant C was linked to increased wool yield and mean staple length, and decreased MFD, fiber diameter standard deviation, and prickle factor, suggesting higher wool quality. These findings indicated potential for breeding programs aimed at improving wool traits by selecting for specific KRTAP26-1 variants.
42 citations
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January 2017 in “Genes” The gene KAP22-1 affects wool yield and fiber shape in sheep.
98 citations
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May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
51 citations
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September 2012 in “Gene” 92 citations
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January 2012 in “International Journal of Biological Sciences” The document introduced a new naming system for keratin-associated proteins to improve clarity and communication across species.
26 citations
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January 2011 in “Open Journal of Genetics” The KAP13-3 gene in sheep affects wool quality by influencing keratin assembly.
50 citations
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July 2008 in “British Journal of Dermatology” 51 citations
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January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
53 citations
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June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” KAP genes show significant genetic variability, but its impact on hair traits is unclear.
226 citations
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January 2002 in “Biological and Pharmaceutical Bulletin” A new method quickly extracts and identifies proteins from hair and other keratin sources.
228 citations
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January 1997 in “Birkhäuser Basel eBooks” Keratin proteins and their genes are crucial for hair growth and structure.