Identification of the Ovine Keratin-Associated Protein 26-1 Gene and Its Association with Variation in Wool Traits

    September 2017 in “ Genes
    Shaobin Li, Huitong Zhou, Hua Gong, Fangfang Zhao, Jiang Hu, Yuzhu Luo, Jon G. H. Hickford
    TLDR Selecting specific KRTAP26-1 gene variants can improve wool quality in sheep.
    The study identified the ovine Keratin-Associated Protein 26-1 (KRTAP26-1) gene and its variants in 383 Merino-Southdown cross sheep, revealing four variants (A-D). Variant B was associated with increased mean fiber diameter (MFD), mean fiber curvature, and prickle factor, while variant C was linked to increased wool yield and mean staple length, and decreased MFD, fiber diameter standard deviation, and prickle factor, suggesting higher wool quality. These findings indicated potential for breeding programs aimed at improving wool traits by selecting for specific KRTAP26-1 variants.
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