Study on the Expression Patterns of Inner Root Sheath-Specific Genes in Tan Sheep Hair Follicle During Different Developmental Stages

    July 2024 in “ Gene ”
    An Shi, Jiangjiang Lv, Qing Ma, Zhanfa Liu, Lina Ma, Junhan Zhou, Jinzhong Tao
    TLDR IRS-specific genes in Tan sheep hair follicles peak at birth and may affect wool crimp.
    This study analyzed the expression patterns of inner root sheath (IRS) specific genes in Tan sheep hair follicles at various developmental stages. Skin samples were collected from male Tan sheep at five stages: 85 and 120 days of fetal development, and 0, 35, and 60 days after birth. The results showed that IRS-specific genes, particularly KRT71, KRT72, and TCHH, had the highest expression levels at birth (D0), which aligns with the wool crimp pattern observed in Tan sheep. This suggests that these genes may influence wool curling by affecting the morphology of the IRS.
    Discuss this study in the Community →

    Research cited in this study

    15 / 15 results

    Related Community Posts Join

    6 / 85 results

      community Going to try and reverse MPB naturally.

      in Treatment  55 upvotes 3 years ago
      A user is trying to reverse male pattern baldness (MPB) naturally by taking high doses of Vitamin D, improving diet, exercising, reducing stress, and other lifestyle changes, but plans to use finasteride if no results are seen in 60 days. Other users are skeptical, advising medical treatments like finasteride and warning against potential vitamin D overdose and the ineffectiveness of natural remedies for genetic hair loss.

      community Balding, short, small penis. What is the point of living…

      in Treatment  405 upvotes 4 years ago
      A 24 year old male struggling with the physical and mental effects of balding, being short, and having a micropenis. Suggested treatments include taking medications such as finasteride and minoxidil, lifting weights, and trying not to compare himself to others.

      community hairloss in my 20s has ruined my life.

      in Research/Science  373 upvotes 7 months ago
      A person in their 20s is struggling with hair loss, using treatments like minoxidil and finasteride. Suggestions include self-improvement, therapy, hair transplants, and focusing on acceptance and confidence.

      community Planning to for Hair transplant

      in Transplants  104 upvotes 1 year ago
      The conversation is about someone considering a hair transplant due to ineffective hair loss treatments, with suggestions ranging from trying a hairpiece to continuing with medications like finasteride and minoxidil, and waiting for new treatments. Some advise against a transplant due to the extent of hair loss and the cost, while others share different views on the effectiveness of transplants and non-surgical options.

      community How uninformed the general public is about hair loss

      in Chat  317 upvotes 1 year ago
      The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

    Related Research

    2 / 2 results