Association Analysis of Polymorphisms in Six Keratin Genes with Wool Traits in Sheep

    November 2017 in “ Asian-Australasian journal of animal sciences ”
    Ablat Sulayman, Mahira Tursun, Yiming Sulaiman, Xixia Huang, Kechuan Tian, Tian Yuan, Xinming Xu, Xuefeng Fu, Amat Mamat, Hanikezi Tulafu
    Image of study
    TLDR Certain gene mutations are linked to wool quality in sheep and could help in breeding for better wool.
    In a study conducted on 418 Chinese Merino (Xinjiang type) sheep, researchers identified 20 mutation sites within six keratin (KRT) genes and analyzed their association with wool traits. Twelve of these mutations were silent, five were missense mutations leading to amino acid changes, two were nonsense mutations, and one was a same-sense mutation. The study found significant associations between specific genotypes of KRT31, KRT36, KRT38, and KRT85 genes and various wool characteristics such as fiber diameter, wool fineness score, and the number of crimps. Additionally, certain combinations of genotypes at KRT36, KRT38, and KRT85 loci showed a greater effect on wool traits. These findings suggest that these KRT genes and their combinations are important for determining wool quality in sheep and could be used to inform breeding programs for improved wool traits.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 153 results

      community Keratin microspheres - breakthrough

      in Research/Science  15 upvotes 1 year ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  11 upvotes 5 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community New & Improved Hair Growth Stack for Maximum Results

      in Treatment  4 upvotes 9 months ago
      A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

      community Go bald/buzzed, fellas. Your life will improve.

      in Chat  227 upvotes 2 months ago
      Buzzing or shaving your head can boost confidence and save money on hair loss treatments. Some prefer treatments like finasteride and minoxidil to maintain their hair.

      community Summary of Procapil video by Haircafe

      in Minoxidil  2 upvotes 3 months ago
      Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

    Similar Research

    5 / 1000+ results