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GlossaryKeratin 85 (KRT85)

protein crucial for hair structure and strength

Keratin 85, also known as KRT85, is a type of protein found in hair follicles. It plays a crucial role in the structure and strength of hair, contributing to its resilience and elasticity. Mutations in the KRT85 gene can lead to hair disorders, such as monilethrix, which is characterized by beaded or fragile hair.

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research Mutations in the Keratin 85 (KRT85/hHb5) Gene Underlie Pure Hair and Nail Ectodermal Dysplasia

42 citations, October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mutations in the KRT85 gene cause hair and nail problems.

research Variation in the Exon 3–4 Region of Ovine KRT85 and Its Effect on Wool Traits

1 citations, August 2024 in “Animals”

KRT85 gene variations can help improve wool traits in sheep through selective breeding.

research Association Analysis of Polymorphisms in Six Keratin Genes with Wool Traits in Sheep

17 citations, November 2017 in “Asian-Australasian journal of animal sciences”

Certain gene mutations are linked to wool quality in sheep and could help in breeding for better wool.

research Identification of the Key Proteins Associated With Different Hair Types in Sheep and Goats

2 citations, September 2022 in “Frontiers in genetics”

Different proteins are linked to the varying thickness of sheep and goat hair types.

research Generation of a Laser Capture Microdissection and RNAseq-Based Human Anagen Hair Follicle Transcriptome Atlas

July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists created a detailed map of gene activity in different parts of human hair follicles.

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