research Association Analysis of Polymorphisms in Six Keratin Genes with Wool Traits in Sheep
Certain gene mutations are linked to wool quality in sheep and could help in breeding for better wool.
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5 / 492 results research Differential Transcriptomics and Metabolomics Analyses of the Skin of Coarse and Fine Liaoning Cashmere Goats
The study examined the relationship between regulatory factors and cashmere fiber diameter in 400 female Liaoning cashmere goats, divided into coarse and fine hair types. Significant differences in fiber diameters were found between the groups. Transcriptomic analysis identified 211 differentially expressed genes, such as FGF18, KRT36, KRT79, AWAT2, and MOGAT1, linked to hair follicle growth and sebum secretion through PPAR and glycerol–lipid metabolism pathways. Metabolomics analysis identified 50 differentially expressed metabolites involved in cellular ion channels and neurological pathways, including ABC transporter protein pathways and arachidonic acid metabolism. These findings could help improve cashmere quality in goats.
research Types I and II Keratin Intermediate Filaments
Keratins are crucial for cell structure, growth, and disease risk.
research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation
A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.
research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle
Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
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