Transcriptome Profile at Different Physiological Stages Reveals Potential Mechanism for Curly Fleece in Chinese Tan Sheep

    August 2013 in “ PloS one ”
    Xiaolong Kang, Gang Liu, Yufang Liu … Meiying Fang
    Studysummary This study suggests that changes in expressed transcripts and splice isoforms may explain the transition from curly to straight fleece in Chinese Tan sheep as they age.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on journals.plos.org →
    Discuss this study in the Community →

    Research cited in this study 15

    1. Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat Skin During Hair Follicle Development and Cycling PloS one · 2013
    2. Cutaneous Retinoic Acid Levels Determine Hair Follicle Development And Downgrowth Journal of biological chemistry/˜The œJournal of biological chemistry · 2012
    3. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011
    4. Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    5. Common Variants in the Trichohyalin Gene Are Associated with Straight Hair in Europeans American journal of human genetics · 2009
    6. Ephrin-A3 Increases Hair Follicle Density and Accelerates Anagen Development in Neonatal Mice Journal of Dermatological Science · 2008
    7. TNF Superfamily in Skin Appendage Development Cytokine & growth factor reviews · 2008
    8. Disruption of P2RY5, an Orphan G Protein–Coupled Receptor, Underlies Autosomal Recessive Woolly Hair Nature genetics · 2008
    9. The Biology of Hair Shape International Journal of Dermatology · 2005
    10. Cytochrome P450: A Target for Drug Development for Skin Diseases ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    11. Different Gene Expression Profile Observed in Dermal Papilla Cells Related to Androgenic Alopecia by DNA Macroarray Analysis Journal of Dermatological Science · 2004
    12. A Small Deletion Hotspot in the Type II Keratin Gene mK6irs1/Krt2-6g on Mouse Chromosome 15, a Candidate for Causing the Wavy Hair of the Caracul (Ca) Mutation Genetics · 2003
    13. A Unique Type I Keratin Intermediate Filament Gene Family Is Abundantly Expressed in the Inner Root Sheaths of Sheep and Human Hair Follicles Journal of Investigative Dermatology · 2001
    14. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996
    15. Analysis of the Sheep Trichohyalin Gene: Potential Structural and Calcium-Binding Roles of Trichohyalin in the Hair Follicle The Journal of Cell Biology · 1993