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This study highlights that hydrogel formulations unexpectedly prolonged healing in trials, pointing to a need for design based on detailed pathophysiological insights rather than empirical methods, and suggests technologies like AI materials optimization and 3D bioprinting to aid their clinical use for cancer survivors.

This article reviews the development milestones of clascoterone up to its first approval for treating acne vulgaris, reporting no new clinical results for androgenetic alopecia.

This review discusses the evolutionary history of keratins and reports no new results, highlighting key events that contributed to the development of mammalian hair and integument.

This review examines the skin manifestations of various endocrine disorders, highlighting their underlying pathophysiology and impact on an individual's health and quality of life, without reporting new research findings.

This study suggests that dietary vitamin A may influence alopecia development and progression, but the mechanisms remain unclear, highlighting the interplay between genetics and nutrition in these hair loss conditions.

This article reviews naevus comedonicus, highlighting potential treatments like retinoic acid application and surgical intervention, but reports no new clinical findings.

This study explores the role of Lgr6⁺ cells in tissue development and repair across different organs and associates abnormal Lgr6 expression with major diseases, including tumors, noting its potential as a therapeutic target for cancer and other conditions.

This study examined the skin transcriptomic differences between Jiangnan and Changthangi cashmere goats, identifying 4,942 differentially expressed genes that may contribute to variations in cashmere quality, with notable enrichment in various signaling pathways and structural components of hair follicles.

This study introduced an innovative antioxidant serum for skin care, using a lipid active from Rana catesbeiana Shaw, and validated its rejuvenating potential through physical-chemical and microbiological tests that ensured its antioxidant effectiveness, microbiological safety, and formulation stability.

This article reviews a tabletop microscopy method for recording electromagnetic radiation from tissues, using hair follicles as a model, and presents no new clinical findings.

This study found that blocking LFA-1 signaling completely prevented the development of alopecia areata in C3H/HeJ mice, suggesting that LFA-1 plays a crucial role in the disease's pathogenesis and could be a target for new therapies.

This study found that extracellular factors from a specific developmental stage can promote hair follicle neogenesis in adult skin by facilitating interactions between fibroblasts and keratinocytes.

The digital system for measuring melasma shows promise but needs more development for better accuracy and automation.

This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.

This study identified a new S100 fused-type protein, scaffoldin, in reptiles and birds and suggests that SFTP-positive epithelia serve as scaffolds for the growth of various skin appendages, indicating a common evolutionary origin.

This study found that the DNA methylation status of skin samples from cashmere goats was higher during the telogen stage compared to the anagen stage, identifying genes potentially important for hair follicle development and growth.

This review highlights how organoid technology is transforming precision medicine by summarizing its development and applications in modeling diseases, testing drug efficacy, and tailoring patient-specific treatments, despite current challenges in standardization and ethical considerations.

In this study, researchers observed that a noncanonical mechanism involving the γ-secretase-dependent, RBPj-independent Notch intracellular domain improves survival in Msx2-Cre mice by delaying hair follicle destruction and reducing disease severity.

In this study, researchers found that the protein Twist2 plays a crucial role in scarless wound healing in early embryonic mouse skins, with its knockdown leading to visible scarring and defective hair follicle formation, suggesting potential therapeutic targets for reducing scars and promoting regeneration.

This study found that cathepsin L deficiency in mice led to significant abnormalities in hair follicle development and cycling, including disrupted hair shaft outgrowth and premature hair growth phase entry.

Skin health and diseases are closely linked to metabolic processes.

This study found that maintaining a low level of Wnt/β-catenin activity is crucial for mammary gland development, as excessive activity inhibits branching and promotes characteristics of hair follicles instead, highlighting its role in skin appendage identity decisions.

A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

This study found that a melatonin-loaded microemulsion exhibited controlled release and significant stratum corneum deposition in ex vivo permeation tests, suggesting its potential for further evaluation in treating androgenic alopecia.

This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.

This study found that scurvy is associated with the development of Sjögren's syndrome symptoms, which resolved with ascorbic acid repletion.

This review discusses the role and plasticity of epidermal stem cells in skin maintenance, wound repair, and cancer, noting recent insights from advanced technologies but providing no new clinical results.

This study demonstrated that human sebaceous glands can be successfully transplanted onto nude mice, where androgen stimulation increases gland volume, cell size, and labeling index.

In this study, Far2-/- mice were observed to develop focal alopecia with altered sebaceous gland morphology and lower skin lipid levels compared to wildtype mice.

This review categorizes contractile hydrogels by their contraction mechanisms and explores their role in advanced wound management, emphasizing mechanical and biochemical signaling in healing, but also notes challenges like force transmission and clinical applicability.