April 2022 in “Molecules” This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.
July 2024 in “Journal of Investigative Dermatology”
3 citations
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January 2021 in “Journal of Bioscience and Bioengineering” In this study, researchers found that sweet potato shochu oil promotes hair growth in both human follicle dermal papilla cells and C3H mice. The oil contains components like ethyl palmitate, ethyl linoleate, and ethyl α-linolenate, which were key contributors to its hair growth-inducing effects.
1 citations
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January 2004 in “Journal of Physiology & Pathology in Korean Medicine” Thuja orientalis extract significantly promotes hair growth in mice with hair loss.
1 citations
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September 2023 in “Applied sciences (Basel)” This study found that Ishige sinicola ethanol extract and its butanol fraction can protect against lipopolysaccharide-induced muscle atrophy in C2C12 myotubes through antioxidant and anti-inflammatory activities.
September 1995 in “Hair transplant forum international” This article discusses the history and recent resurgence of Japanese hair replacement surgery but provides no new clinical findings.
1 citations
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December 2022 in “International Journal of Science for Global Sustainability” This study found that Mitracarpus hirtus extracts showed potential antifungal activity against Tinea capitis in vitro, with ethylacetate extracts demonstrating the highest inhibitory effects.
July 2025 in “JURNAL BIOLOGI TROPIS” In this animal study, the researchers reported that a shampoo containing 2.5% teak leaf extract and 0.30% virgin coconut oil significantly increased hair growth rate and reduced hair loss in mice, suggesting potential benefits for addressing hair loss.
December 2023 in “Journal of dispersion science and technology” This study introduced a natural shampoo formulation containing Gleditsia sinensis Lam extract, Sapindus mukurossi extract, and other ingredients, which demonstrated effective foaming, antioxidant, antibacterial, and antifungal properties.
In this case report, interferon-alpha treatment for a man with hemophilia and hepatitis C was associated with unexpected diffuse hair growth, likely caused by the medication.
January 2026 in “Applied Biological Chemistry” This study found that Ishophloroglucin A from brown seaweed may treat androgenic alopecia by inhibiting 5α-reductase and promoting hair growth-related factors in human dermal papilla cells.
January 2010 in “World Journal of Integrated Traditional and Western Medicine” This study found that after 12 months, the combination of shengfa tincture and dangui kushen pills was more effective and had fewer adverse effects for treating androgenetic alopecia compared to shengfa tincture alone.
July 2022 in “Siriraj Medical Bulletin” This study developed a hair conditioner incorporating shogun orange peel extract, which was found to strengthen and smooth hair, enhance elasticity, and was well-received by users, as evidenced by a high satisfaction rating of 4.40 out of 5.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This case report describes a 33-year-old male with treatment-resistant psoriasis who experienced complete resolution of symptoms and hair regrowth after following an integrated Shodhana-Shamana chikitsa regimen, with no relapse noted at follow-up, suggesting its potential for sustainable Ekakustha management.
4 citations
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May 2014 in “Daehan hanbang so'a'gwa haghoeji/Daehan hanbang soagwa hakoeji” In this study, Ganoderma lucidum extract combined with microneedle therapy promoted hair growth more effectively than microneedle therapy alone in a mouse model of alopecia.
1 citations
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July 2023 in “Chinese Medicine” This study found that Shi-Bi-Man significantly promotes hair regeneration in cynomolgus monkeys by increasing hair follicle stem cells and up-regulating metabolic pathways.
November 2024 in “Traditional & Kampo Medicine” This study found that kumazasa extract promotes hair growth in a mouse model and human hair follicle cells, with effects similar to minoxidil, but it did not cause the inflammation observed with minoxidil use.
July 1996 in “Hair transplant forum international” This meeting summary reports on a gathering of the Japanese Society with presentations primarily in Japanese and provides no new scientific findings.
17 citations
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January 2009 in “Nippon Ishinkin Gakkai Zasshi” This case report details a 10-year-old boy diagnosed with kerion celsi caused by Microsporum gypseum, successfully treated with itraconazole over 4.5 months.
February 2023 in “Journal of dermatology” This letter reports the first known Japanese case of autosomal recessive woolly hair/hypotrichosis with compound heterozygous mutations in the LIPH gene.
64 citations
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March 2006 in “Food Chemistry” In castrated rats, this study found that triterpenoids from Ganoderma lucidum inhibited both types of 5α-reductase and reduced prostate growth linked to testosterone but not dihydrotestosterone.
September 2024 in “BMJ Case Reports” This case report highlights an atypical presentation of favus in an immunocompetent adult, where a psoriasiform plaque over the 'bindi' area was successfully treated with systemic itraconazole, achieving complete resolution without relapse. Simple stains proved essential for diagnosis in this resource-limited setting.
2 citations
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August 2018 in “Korean Journal of Plant Resources” This study found that oregonin, isolated from Alnus japonica, demonstrated strong antioxidant activity and apoptosis modulation in hair follicle cells, suggesting its potential as a natural ingredient for preventing hair loss in cosmetic products.
May 2025 in “Phytomedicine” Qu-shi-yu-fa Decoction may help treat hair loss by promoting hair growth and strengthening.
26 citations
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November 2002 in “Planta medica” In this study, the methanol extract of Cercidiphyllum japonicum heartwood was found to stimulate the proliferation of mouse hair epithelial cells, with several isolated compounds showing significant proliferative activities.
2 citations
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January 2024 in “Journal of Pharmacognosy and Phytochemistry” The study highlights Teak's (Tectona grandis) diverse applications beyond high-quality timber, emphasizing its bioactive compounds' pharmacological potential in cancer treatment and other uses across traditional medicine, cosmetics, and biodiesel production.
12 citations
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January 1988 in “YAKUGAKU ZASSHI” This study found that Polygonum multiflorum and Panax japonicum extracts could promote hair regrowth in mice, suggesting potential use as hair tonics.
March 2015 in “Hair transplant forum international” This article provides an overview of the 19th Annual Scientific Meeting and Live Surgery Workshop of the Japan Society of Clinical Hair Restoration and reports no new research findings.
3 citations
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January 2017 in “Evidence-based complementary and alternative medicine” This study found that Galla chinensis solution significantly improved skin lesions and fungal eradication in dermatophytosis-infected dogs, showing over 85% efficacy in fungal removal after 14 days and outperforming the positive control treatment.
4 citations
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March 2021 in “Asian Journal of Beauty and Cosmetology” This study found that Dendropanax, sea salt, spinach, and kelp were safe and potentially effective as ingredients in functional cosmetics aimed at alleviating hair loss symptoms.