808 Lichen Planus Single Cell and Spatial Profiling of Cutaneous Lichen Planus Treated with Baricitinib

Results are not reported in this article by Zizhuo Li et al. on baricitinib as a treatment for lichen planopilaris.

In this case study, a patient with refractory oral lichen planus experienced marked improvement within one month of daily treatment with baricitinib, contributing to the evidence supporting the use of JAK inhibitors for lichen planus.

In this research, RNA expression analysis of scalp biopsies from lichen planopilaris patients revealed changes in specific genes after treatments with hydroxychloroquine, narrow band UVB, or low level laser light therapy, suggesting potential biomarkers and implicating M2 macrophages in the disease's immunopathogenesis.

This article discusses alopecia areata and lichen planopilaris, providing a review of their clinical characteristics and reporting no new research findings; the authors underscore the potential progression and distinctive features of each condition.