Efficacy and Safety of Tofacitinib in the Treatment of Adults with Lichen Planopilaris: A Randomized Placebo-Controlled Trial
July 2025
in “
International Immunopharmacology
”
Research cited in this study
9 / 9 results
research Positive Anagen Pull Test Predicting Lichen Planopilaris Activity
This study found that a positive anagen pull test can be an indicator of lichen planopilaris activity, suggesting its utility in the clinical assessment of this condition.
research Lichen Planopilaris and Frontal Fibrosing Alopecia: Review and Update of Diagnostic and Therapeutic Features
This comprehensive literature review highlighted that lichen planopilaris and frontal fibrosing alopecia, both primary scarring alopecias, are diagnosed via scalp biopsy, with no standardized treatments available, necessitating individualized therapeutic approaches based on patient characteristics.
research Diffuse Variants of Scalp Lichen Planopilaris: Clinical, Trichoscopic, and Histopathologic Features of 40 Patients
This study reviewed 40 patients with scalp symptoms and identified a new variant of diffuse lichen planopilaris in 20 individuals, suggesting these conditions should be considered in similar cases.
research Lichen Planopilaris: Retrospective Study on the Characteristics and Treatment of 291 Patients
In a study reviewing 291 patients with lichen planopilaris, findings revealed that women were more commonly affected than men, cyclosporine and methotrexate were most effective in achieving remission, and 5-alpha reductase inhibitors and systemic retinoids were particularly beneficial for frontal fibrosing alopecia.
research Algorithmic Approach to the Treatment of Frontal Fibrosing Alopecia: A Systematic Review
This study evaluated treatments for frontal fibrosing alopecia and found hydroxychloroquine and 5a-reductase inhibitors to be most effective, with 70-72% of patients experiencing stabilization or improvement, but limitations in treatment consistency and assessment methods remain.
research Tofacitinib for the Treatment of Lichen Planopilaris: A Case Series
This study found that treatment with oral tofacitinib, alone or with other therapies, was associated with clinical improvement in most patients with recalcitrant lichen planopilaris.
research Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review
This study reported that while no effective treatment exists for frontal fibrosing alopecia, oral 5-alpha-reductase inhibitors showed the most promise, inducing a good clinical response in 45% of patients.
research Commentary: Treatment of Lichen Planopilaris
This article discusses the efficacy and safety of mycophenolate mofetil and hydroxychloroquine for treating lichen planopilaris and reports no new clinical results.
research Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component
This article reviews lichen planopilaris, a chronic scarring alopecia, and explores recent treatment developments, but it reports no new clinical results.
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research 491 Efficacy of oral tofacitinib in the treatment of lichen planopilaris
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research Efficacy and Safety of Tofacitinib in Lichen Planopilaris: A Retrospective Series of 74 Patients
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research Tofacitinib for the treatment of lichen planopilaris: A case series
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research Topical tofacitinib for patients with lichen planopilaris and/or frontal fibrosing alopecia
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