Effects of Ganoderma Lucidum Extract and Microneedle Therapy on Hair Growth in an Alopecia Model of C57BL/6N Mice

May 2014 in “ Daehan hanbang so'a'gwa haghoeji/Daehan hanbang soagwa hakoeji ”

Bong Hyun Ju, Sun Yu, Kyung‐Hwa Kang, Seung Yoen Lee

Ganoderma lucidum extract microneedle therapy system alopecia hair growth hair density hair thickness hair length hair follicles root growth hair growth-related genes hair growth-related proteins GLE MTS

Studysummary In this study, Ganoderma lucidum extract combined with microneedle therapy promoted hair growth more effectively than microneedle therapy alone in a mouse model of alopecia. Our plain-language summary of this paper — not a Tressless recommendation.

This study investigated the effects of Ganoderma lucidum extract (GLE) and microneedle therapy system (MTS) on hair growth in C57BL/6N mice with alopecia. Mice were divided into four groups and treated twice a week for 3 weeks. Results showed that both GLE + MTS and MTS alone promoted hair growth, with improvements in hair density, thickness, and length compared to the control group. Additionally, the expression of hair growth-related genes and proteins was increased, and hair follicles and root growth were enhanced. GLE + MTS was found to be more effective than MTS alone, suggesting potential for alopecia treatment.

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