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This study found that serum metabolic profiles differ significantly between polycystic ovary syndrome patients and healthy controls, highlighting potential metabolic markers for diagnosing and prognosing PCOS.

This study identified distinct metabolic differences between PCOS patients and healthy controls, suggesting potential metabolic markers for PCOS prognosis and diagnosis.

In this study, researchers observed that dietary vitamin D intake and light exposure play a crucial role in vitamin D metabolism in mice, suggesting similar importance for human health in maintaining optimal vitamin D levels.

This study used Mendelian randomization analysis to identify Scyllo-inositol and Alpha-ketoglutarate as potential protective factors and Heme and 2-palmitoylglycerophosphocholine as risk factors for androgenic alopecia, suggesting a causal link between these metabolites and the condition.

Men with androgenetic alopecia have unique metabolomic patterns that could help develop targeted treatments.

This study found that monitoring endogenous steroid metabolites in serum may improve the detection of testosterone doping by highlighting promising biomarkers.

This study suggests potential causal links between blood levels of glutamine, citric acid, glucose, various lipids, and lipoproteins with alopecia areata, finding glutamine may have a protective effect and noting no evidence of reverse causality. Further research is needed to validate these associations.

This study reports a solid causal relationship between increased serum levels of ApoB, LDL, and VLDL and an elevated risk of androgenic alopecia.

This study suggests that while hair analysis using GC-MS is a sensitive method for detecting cocaine ingestion, it may not reliably indicate the amount, timing, or duration of drug use due to interindividual variability and multiple incorporation mechanisms.

Copper may protect against alopecia areata, while certain inflammatory markers increase risk.

This study found that diagnosing non-classical 3 beta-hydroxysteroid dehydrogenase deficiency solely based on elevated serum or urinary 5-ene-steroids may not be reliable.

Kidney stones and hair loss are significantly related in people under 60 years old.

In this study, females with 5 alpha-reductase-2 deficiency exhibited decreased body hair, normal sebum production, and delayed menarche, suggesting a role for DHT in hair growth and menstrual function.

In this study, correlations between urinary and serum androgen metabolites were examined in girls aged 6-13, revealing that summed urinary metabolites strongly correspond with circulating androstenedione and testosterone levels, though individual variations depend on participant characteristics such as age and body measurements.

This study found that serum prolactin and dehydroepiandrosterone levels did not determine the onset of mink hair growth cycles, though their metabolites may influence other aspects of hair growth.

This case report describes a man who ingested a large amount of topical minoxidil solution and experienced serious and prolonged cardiovascular effects despite rapidly decreasing serum concentration levels.

This article reviews the role of vitamin D and its metabolites in regulating calcium homeostasis and highlights their effects on the intestine, kidney, bone, and parathyroid gland, without reporting new clinical results.

This study found that caucasian subjects had higher serum levels of 5 alpha-reduced androgen metabolites compared to Chinese subjects, suggesting racial differences in 5 alpha-reductase activity and a potential mechanism for increased body hair in caucasian men.

This study found significant differences in cashmere fiber diameters between two groups of cashmere goats and identified 211 genes and 50 metabolites related to hair follicle growth and cellular functions, suggesting potential pathways to improve cashmere quality.

This study found that administering the gut bacterium Thauera sp. strain GDN1 to mice significantly reduced their serum androgen levels, indicating gut bacteria may influence androgen metabolism.

In this study, COC treatment led to greater improvements in sex hormone, endocrine factor, and metabolic levels among PCOS patients compared to those who did not receive the treatment.

In this study, distinct metabolic profiles were identified in women with PCOS, suggesting potential biomarkers for diagnosis based on changes in lipid and androgen metabolism.

This study concluded that steroid deficiencies were significantly more severe in men with panhypopituitarism than in those with isolated gonadotropin deficiency.

This study found that in women with acne vulgaris, lower serum levels of 3α-androstanediol-glucuronide suggest reduced 5α-reductase activity compared to controls, indicating that 5α-reductase inhibitors may not be effective for acne treatment.

In this study, AGA patients exhibited distinct lipidomic profiles and higher metabolic syndrome prevalence compared to controls, with certain lipids correlated to key AGA-related factors like DHT, PGD2, and TGF-β1.

This study observed that simvastatin promoted hair regrowth in a mouse model of alopecia areata by reducing inflammatory markers and T cell proliferation, partly through disruption of isoprenoid metabolite production.

This study demonstrated that GP derivatization improves mass spectral analysis of spironolactone and its metabolites by reducing in-source fragmentation and enhancing signal clarity, laying the groundwork for future advancements in reaction optimization and quantitative assay development.

This study suggests that hepatocellular carcinoma in cirrhotic men is associated with altered sex-steroid metabolism, indicated by lower testosterone and 5 alpha-dihydrotestosterone levels compared to cirrhosis alone.

This case report describes a woman with hyperandrogenism and menstrual disturbances, where an ovarian steroid cell tumor was identified and removed, leading to resolution of symptoms.

This study identified 18 significant metabolites and two enriched metabolic pathways, necroptosis and ABC transporters, in serum samples of acne patients with and without insulin resistance, potentially aiding in the clinical diagnosis and drug development for these patients.