Targeted Delivery of Zinc Pyrithione to Skin Epithelia

    Sean E. Mangion, Amy Holmes, Michael S. Roberts
    TLDR Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
    The document discusses the targeted delivery of zinc pyrithione (ZPT) to skin epithelia for treating dandruff and seborrheic dermatitis. It highlights ZPT's antimicrobial properties against Malassezia yeasts, which are implicated in these scalp conditions. Various studies and clinical trials demonstrate ZPT's efficacy in reducing dandruff symptoms and improving scalp health. The paper also explores ZPT's pharmacokinetics and mechanisms of action, emphasizing its role in maintaining the stratum corneum's barrier function and reducing inflammation. The conclusion is that ZPT is a potent and effective treatment for dandruff and related scalp disorders.
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      community is this good ? did anyone try it ?

      in Ketoconazole  4 upvotes 11 months ago
      Ketoconazole is discussed as a treatment for hair loss, with mixed reviews on its effectiveness and side effects. Some users find it helpful for scalp conditions, while others report it makes hair feel dry and doesn't aid regrowth.

      community Shoutout to Zinc pyrithione and Piroctone olamine

      in Product  3 upvotes 7 months ago
      Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.

      community Hot weather causing hair shedding?

      in Minoxidil  3 upvotes 1 week ago
      Hot weather can increase hair shedding, possibly due to dehydration and active sebaceous glands. Using shampoos with salicylic acid or zinc pyrithione may help; daily anti-inflammatory use is not recommended.

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