Targeted Delivery of Zinc Pyrithione to Skin Epithelia

    Sean E. Mangion, Amy Holmes, Michael S. Roberts
    TLDR Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.
    The document discusses the targeted delivery of zinc pyrithione (ZPT) to skin epithelia for treating dandruff and seborrheic dermatitis. It highlights ZPT's antimicrobial properties against Malassezia yeasts, which are implicated in these scalp conditions. Various studies and clinical trials demonstrate ZPT's efficacy in reducing dandruff symptoms and improving scalp health. The paper also explores ZPT's pharmacokinetics and mechanisms of action, emphasizing its role in maintaining the stratum corneum's barrier function and reducing inflammation. The conclusion is that ZPT is a potent and effective treatment for dandruff and related scalp disorders.
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      community is this good ? did anyone try it ?

      in Ketoconazole  4 upvotes 2 weeks ago
      Ketoconazole is discussed as a treatment for hair loss, with mixed reviews on its effectiveness and side effects. Some users find it helpful for scalp conditions, while others report it makes hair feel dry and doesn't aid regrowth.

      community 2 months on topical min and fin.

      in Progress Pictures  1 upvotes 6 months ago
      The user has been using topical Minoxidil (5%) and finasteride (0.1%) twice daily for 2 months, with occasional missed applications. They also use a zinc pyrithione shampoo every 2 days and do not dermaroll.

      community 15months hair regrowth results

      in Progress Pictures  6 upvotes 1 year ago
      The user saw hair regrowth after inconsistently using treatments like microneedling, peppermint and rosemary oils, ketoconazole shampoo, zinc pyrithione shampoo, and scalp massages, but stopped minoxidil due to heart palpitations. They plan to start a consistent treatment with a minoxidil and finasteride topical solution and will share results in six months.

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