Stratum Corneum Dysfunction in Dandruff

    April 2012 in “ International Journal of Cosmetic Science ”
    G. A. Turner, Michael Hoptroff, Clive R. Harding
    Image of study
    TLDR Improving skin barrier and using antifungal treatments can help manage dandruff.
    The review article discussed the multifactorial etiology of dandruff, emphasizing the role of the commensal yeast Malassezia, sebum production, and individual susceptibility. It highlighted that a compromised stratum corneum (SC) barrier leads to increased transepidermal water loss, subclinical inflammation, and higher susceptibility to irritants. The review proposed that improving SC integrity alongside antifungal treatments could be beneficial for managing dandruff. Effective antidandruff treatments aim to restore scalp health by reducing Malassezia levels and facilitating flake removal. Advanced shampoos combining mild surfactants, direct barrier lipid replenishment, and antimicrobial activity were suggested to optimize scalp health in individuals with dandruff.
    Discuss this study in the Community →

    Research cited in this study

    3 / 3 results

    Related Community Posts Join

    6 / 16 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community A Different Take on Curing MBP

       16 upvotes 5 years ago
      Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

      community Trying to regrow crown been on Fin for 4.5 years

      in Finasteride/Dutasteride  6 upvotes 7 months ago
      The user has been on finasteride for 4.5 years and minoxidil for 10 years, maintaining hair but not regrowing much on the crown and temples. They are considering using a dermastamp more frequently and possibly trying RU58841, but are hesitant about dutasteride due to concerns about side effects and DHT suppression.

      community Why do I see so many people here recommend microneedling?

      in Microneedling  105 upvotes 1 year ago
      The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.

      community Dr Kyle Gillett on topical Dutasteride

      in Finasteride/Dutasteride  56 upvotes 2 years ago
      The potential effectiveness of topical dutasteride, as well as other hair loss treatments such as finasteride, RU58841, minoxidil, and various vitamins. Experiences from users who have used these treatments were shared.

    Similar Research

    5 / 1000+ results