Stratum Corneum Dysfunction in Dandruff

    April 2012 in “ International Journal of Cosmetic Science ”
    G. A. Turner, Michael Hoptroff, Clive R. Harding
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    TLDR Improving skin barrier and using antifungal treatments can help manage dandruff.
    The review article discussed the multifactorial etiology of dandruff, emphasizing the role of the commensal yeast Malassezia, sebum production, and individual susceptibility. It highlighted that a compromised stratum corneum (SC) barrier leads to increased transepidermal water loss, subclinical inflammation, and higher susceptibility to irritants. The review proposed that improving SC integrity alongside antifungal treatments could be beneficial for managing dandruff. Effective antidandruff treatments aim to restore scalp health by reducing Malassezia levels and facilitating flake removal. Advanced shampoos combining mild surfactants, direct barrier lipid replenishment, and antimicrobial activity were suggested to optimize scalp health in individuals with dandruff.
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