Stratum Corneum Dysfunction in Dandruff

    April 2012 in “ International Journal of Cosmetic Science ”
    G. A. Turner, Michael Hoptroff, Clive R. Harding
    Image of study
    TLDR Improving skin barrier and using antifungal treatments can help manage dandruff.
    The review article discussed the multifactorial etiology of dandruff, emphasizing the role of the commensal yeast Malassezia, sebum production, and individual susceptibility. It highlighted that a compromised stratum corneum (SC) barrier leads to increased transepidermal water loss, subclinical inflammation, and higher susceptibility to irritants. The review proposed that improving SC integrity alongside antifungal treatments could be beneficial for managing dandruff. Effective antidandruff treatments aim to restore scalp health by reducing Malassezia levels and facilitating flake removal. Advanced shampoos combining mild surfactants, direct barrier lipid replenishment, and antimicrobial activity were suggested to optimize scalp health in individuals with dandruff.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 26 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community A Different Take on Curing MBP

       16 upvotes 7 years ago
      Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

      community Trying to regrow crown been on Fin for 4.5 years

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The user has been on finasteride for 4.5 years and minoxidil for 10 years, maintaining hair but not regrowing much on the crown and temples. They are considering using a dermastamp more frequently and possibly trying RU58841, but are hesitant about dutasteride due to concerns about side effects and DHT suppression.

      community Dr Kyle Gillett on topical Dutasteride

      in Finasteride/Dutasteride  56 upvotes 3 years ago
      The potential effectiveness of topical dutasteride, as well as other hair loss treatments such as finasteride, RU58841, minoxidil, and various vitamins. Experiences from users who have used these treatments were shared.

      community Tretinoin can make it worse!!!

      in Chat  7 upvotes 2 years ago
      Tretinoin may enhance minoxidil's effectiveness for those not responding to minoxidil alone, but it could reduce efficacy for some who are already responding to minoxidil. Tretinoin requires careful use, including skin moisturizing and sun protection due to increased sensitivity.

    Similar Research

    5 / 1000+ results