Stratum Corneum Dysfunction in Dandruff
May 2012
in “
International Journal of Cosmetic Science
”
stratum corneum dandruff Malassezia sebum production antifungal treatments transepidermal water loss subclinical inflammation antidandruff treatments scalp health flake removal mild surfactants barrier lipid replenishment antimicrobial activity SC yeast fungal treatments water loss inflammation dandruff treatments scalp care shampoo lipid replenishment antimicrobial
TLDR Improving skin barrier and using antifungal treatments can help manage dandruff.
The review article discussed the multifactorial etiology of dandruff, emphasizing the role of the commensal yeast Malassezia, sebum production, and individual susceptibility. It highlighted that a compromised stratum corneum (SC) barrier leads to increased transepidermal water loss, subclinical inflammation, and higher susceptibility to irritants. The review proposed that improving SC integrity alongside antifungal treatments could be beneficial for managing dandruff. Effective antidandruff treatments aim to restore scalp health by reducing Malassezia levels and facilitating flake removal. Advanced shampoos combining mild surfactants, direct barrier lipid replenishment, and antimicrobial activity were suggested to optimize scalp health in individuals with dandruff.
