New Insights on Dandruff/Seborrhoeic Dermatitis: The Role of the Scalp Follicular Infundibulum in Effective Treatment Strategies

The study explored the role of the scalp follicular infundibulum in treating dandruff/seborrhoeic dermatitis (D/SD) and found that effective treatment requires delivering antifungal agents, like zinc pyrithione (ZPT), to this specific area. Researchers developed three methods to measure ZPT delivery to the infundibulum and discovered that commercial ZPT shampoos effectively target this space, reducing Malassezia yeast populations. The particle size of ZPT was identified as a crucial factor for efficient delivery, highlighting the importance of targeting both the scalp surface and infundibulum for effective D/SD treatment.