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GlossaryTransepidermal Water Loss

water evaporates from the skin's surface, indicating barrier function

Transepidermal Water Loss (TEWL) refers to the process by which water passes from the inside of the body through the epidermis (the outermost layer of the skin) and evaporates into the environment. It is a key indicator of the skin's barrier function; higher TEWL values suggest a compromised skin barrier, which can lead to dryness, irritation, and conditions like eczema.

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research Circadian Rhythms on Skin Function of Hairless Rats: Light and Thermal Influences

8 citations , March 2014 in “Experimental Dermatology”

Light and temperature affect the daily skin function rhythms in hairless rats, with temperature influencing water loss but not skin hydration.

Amelioration of Symptoms of Dry and Eczema-Prone Skin by an Oil-in-Water Emulsion Containing a Combination of Zingiber Officinale Root Extract and CBD with Antioxidative and Anti-Inflammatory Activity In Vitro

research Amelioration of Symptoms of Dry and Eczema-Prone Skin by an Oil-in-Water Emulsion Containing a Combination of Zingiber Officinale Root Extract and CBD with Antioxidative and Anti-Inflammatory Activity In Vitro

April 2023 in “Journal of Investigative Dermatology”

An oil-in-water emulsion with CBD and ginger root extract significantly improved symptoms of dry and eczema-prone skin.

Skin Manifestations and Biophysical Properties in Patients With Morbid Obesity and Changes After Weight Loss: A Two-Year Prospective Study

research Skin Manifestations and Biophysical Properties in Patients With Morbid Obesity and Changes After Weight Loss: A Two-Year Prospective Study

April 2023 in “Journal of Investigative Dermatology”

Weight loss surgery improved several skin conditions in obese patients but often caused hair loss.

research The Effect of a Novel Zinc Pyrithione Hair Care System on Female Scalp Condition

February 2013 in “Journal of the American Academy of Dermatology”

The zinc pyrithione hair care system improves scalp hydration and reduces water loss.

research Artificial Intelligence-Based Personalization of Treatment Regimen for Hair Loss: A 6-Month Clinical Trial

March 2025 in “PubMed”

AI-personalized hair loss treatments improved hair growth and scalp health without side effects.

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community Has anybody tried retinol (not Retin A aka tretinoin) combined with minoxidil?

in Treatment 21 upvotes 2 years ago

The conversation is about someone who had success using retinol with minoxidil for hair growth, but experienced shedding with Retin A (tretinoin). They are asking if others have tried retinol with minoxidil and what their results were.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 10 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.