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    Glossary Transepidermal Water Loss

    water evaporates from the skin's surface, indicating barrier function

    Transepidermal Water Loss (TEWL) refers to the process by which water passes from the inside of the body through the epidermis (the outermost layer of the skin) and evaporates into the environment. It is a key indicator of the skin's barrier function; higher TEWL values suggest a compromised skin barrier, which can lead to dryness, irritation, and conditions like eczema.

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    1. Effects of dietary camelina, flaxseed, and canola oil supplementation on inflammatory and oxidative markers, transepidermal water loss, and coat quality in healthy adult dogs Frontiers in Veterinary Science · 2023 · 7 citations
    2. LB948 AI-based customization in hair loss treatment: A 6-month clinical trial with transepidermal water loss and scanning electron microscopy analysis Journal of Investigative Dermatology · 2024
    3. 393 Skin manifestations and biophysical properties in patients with morbid obesity and changes after weight loss: A two-year prospective study Journal of Investigative Dermatology · 2023
    4. 599 Amelioration of symptoms of dry and eczema-prone skin by an oil-in-water emulsion containing a combination of a zingiber officinale root extract and cbd with antioxidative and anti-inflammatory activity in vitro Journal of Investigative Dermatology · 2023
    5. Artificial Intelligence-Based Personalization of Treatment Regimen for Hair Loss: A 6-Month Clinical Trial. PubMed · 2025
    6. Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation 2014 · 32 citations
    7. 25 Hydroxyvitamin D 1 α-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis 2004 · 140 citations
    8. Stratum corneum dysfunction in dandruff International Journal of Cosmetic Science · 2012 · 93 citations
    9. Obesity resistance of the stearoyl-CoA desaturase-deficient (<i>scd1</i> <sup>-/-</sup>) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation Biological Chemistry · 2007 · 87 citations
    10. Epidermal pigmentation in the human lineage is an adaptation to ultraviolet radiation 2013 · 62 citations
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