Search
for

    Glossary Transepidermal Water Loss

    water evaporates from the skin's surface, indicating barrier function

    Transepidermal Water Loss (TEWL) refers to the process by which water passes from the inside of the body through the epidermis (the outermost layer of the skin) and evaporates into the environment. It is a key indicator of the skin's barrier function; higher TEWL values suggest a compromised skin barrier, which can lead to dryness, irritation, and conditions like eczema.

    Related Terms

    Sort by

    Research 30 of 939

    1. Effects of dietary camelina, flaxseed, and canola oil supplementation on inflammatory and oxidative markers, transepidermal water loss, and coat quality in healthy adult dogs Frontiers in Veterinary Science · 2023 · 7 citations
    2. LB948 AI-based customization in hair loss treatment: A 6-month clinical trial with transepidermal water loss and scanning electron microscopy analysis Journal of Investigative Dermatology · 2024
    3. 393 Skin manifestations and biophysical properties in patients with morbid obesity and changes after weight loss: A two-year prospective study Journal of Investigative Dermatology · 2023
    4. 599 Amelioration of symptoms of dry and eczema-prone skin by an oil-in-water emulsion containing a combination of a zingiber officinale root extract and cbd with antioxidative and anti-inflammatory activity in vitro Journal of Investigative Dermatology · 2023
    5. Artificial Intelligence-Based Personalization of Treatment Regimen for Hair Loss: A 6-Month Clinical Trial. PubMed · 2025
    6. Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation 2014 · 32 citations
    7. 25 Hydroxyvitamin D 1 α-Hydroxylase Is Required for Optimal Epidermal Differentiation and Permeability Barrier Homeostasis 2004 · 140 citations
    8. Stratum corneum dysfunction in dandruff International Journal of Cosmetic Science · 2012 · 93 citations
    9. Obesity resistance of the stearoyl-CoA desaturase-deficient (<i>scd1</i> <sup>-/-</sup>) mouse results from disruption of the epidermal lipid barrier and adaptive thermoregulation Biological Chemistry · 2007 · 87 citations
    10. Epidermal pigmentation in the human lineage is an adaptation to ultraviolet radiation 2013 · 62 citations
    11. Antioxidant and Cytoprotective Properties of Plant Extract from Dry Flowers as Functional Dyes for Cosmetic Products Molecules · 2021 · 48 citations
    12. Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production Journal of Investigative Dermatology · 2019 · 40 citations
    13. An investigation of in vivo wound healing activity of biologically synthesized silver nanoparticles Journal of Nanoparticle Research · 2014 · 40 citations
    14. Age-Related Changes in Male Skin: Quantitative Evaluation of One Hundred and Fifty Male Subjects Skin Pharmacology and Physiology · 2013 · 40 citations
    15. Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure The Journal of Pathology · 2016 · 38 citations
    16. Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation Journal of Allergy and Clinical Immunology · 2019 · 34 citations
    17. Caffeine improves barrier function in male skin International Journal of Cosmetic Science · 2006 · 33 citations
    18. Sequential Scalp Assessment in Hair Regeneration Therapy Using an Adipose-Derived Stem Cell–Conditioned Medium Dermatologic Surgery · 2019 · 33 citations
    19. The acyl-CoA binding protein is required for normal epidermal barrier function in mice Journal of Lipid Research · 2012 · 31 citations
    20. Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation Scientific Reports · 2017 · 27 citations
    21. Menopause, skin and common dermatoses. Part 2: skin disorders Clinical and Experimental Dermatology · 2022 · 25 citations
    22. The risk of hydroquinone and sunscreen over-absorption via photodamaged skin is not greater in senescent skin as compared to young skin: Nude mouse as an animal model International journal of pharmaceutics · 2014 · 18 citations
    23. Non-invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases—A Focus on Psoriasis and Lupus erythematosus Frontiers in Immunology · 2019 · 17 citations
    24. Acyl-CoA binding protein and epidermal barrier function Biochimica and biophysica acta. Molecular and cell biology of lipids · 2014 · 15 citations
    25. Coumarin derivatives, but not coumarin itself, cause skin irritation via topical delivery Toxicology Letters · 2014 · 15 citations
    26. Male skin and ingredients relevant to male skin care 2012 · 15 citations
    27. Efficacy of Korean Red Ginseng in the Treatment of Atopic Dermatitis Journal of Ginseng Research · 2011 · 15 citations
    28. Scalp Biophysical Characteristics in Males with Androgenetic Alopecia: A Comparative Study with Healthy Controls Clinical Interventions in Aging · 2021 · 12 citations
    29. Evaluation of changes in skin biophysical parameters and appearance after pneumatic injections of non-cross-linked hyaluronic acid in the face Journal of cosmetic and laser therapy · 2018 · 11 citations
    30. Hair removal and bioavailability of chemicals: Effect of physicochemical properties of drugs and surfactants on skin permeation ex vivo International Journal of Pharmaceutics · 2019 · 10 citations