Application of PLGA Nanostructures to Cosmetics

January 2019 in “ Springer eBooks ”

Yasunaru Kawashima

PLGA nanospheres VC-IP antioxidant DNA damage NanoCrysphere whitening anti-aging ceramide transepidermal water loss TEWL anti-acne agents hinokitiol hair follicles PLGA NS Vitamin C derivative anti-acne hair growth

TLDR PLGA nanospheres in cosmetics improve skin and hair treatment effectiveness.

The document discussed the application of PLGA nanospheres (NSs) in cosmetics, highlighting their effectiveness in delivering active ingredients deep into the skin and hair follicles. VC-IP-loaded PLGA NS emulsions were shown to inhibit DNA damage in skin biopsies due to their antioxidant properties. Products like "NanoCrysphere®" were developed for whitening and anti-aging, while foundations containing ceramide-encapsulated PLGA NSs improved skin moisture and reduced transepidermal water loss (TEWL). Additionally, a compacted powder product efficiently delivered anti-acne agents, and hinokitiol, a hair-growth ingredient, was more effectively delivered to hair follicles using PLGA NS suspensions compared to conventional methods.

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