Psychological Aspects of Hyperandrogenic States in Late Adolescent and Young Women

    March 2015 in “ Clinical Endocrinology ”
    Jenny Guidi, Alessandra Gambineri, Laura Zanotti, Flaminia Fanelli, Giovanni A. Fava, Renato Pasquali
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    TLDR Young women with high male hormone levels or PCOS often feel more psychological distress and have a lower quality of life.
    In a 2015 study involving 835 high school female students aged 16-19, with 394 providing additional laboratory tests, it was found that those with isolated clinical hyperandrogenism and polycystic ovary syndrome (PCOS) experienced significantly higher levels of psychological distress, lower well-being, and quality of life compared to healthy controls. Women with isolated clinical hyperandrogenism showed higher scores for depressive and anxiety symptoms, while those with PCOS exhibited more hostility/irritability. The study highlights the importance of early recognition and management of psychological distress in young women with hyperandrogenic states to improve their psychosocial health and therapy adherence.
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