Hirsutism, Acne, and Hair Loss: Management of Hyperandrogenic Cutaneous Manifestations of Polycystic Ovary Syndrome

    Cenk Yasa, Ozlem Dural, Ercan Bastu, Funda Gungor Ugurlucan
    Studysummary This review outlines the diagnostic criteria and management strategies for polycystic ovary syndrome, focusing on hyperandrogenism's cutaneous manifestations, such as hirsutism and acne, and describes treatments like oral contraceptives and antiandrogens to address these issues.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 34

    1. Prevalence of Androgenic Alopecia in Patients with Polycystic Ovary Syndrome and Characterization of Associated Clinical and Biochemical Features Fertility and Sterility · 2014
    2. How to Diagnose and Treat Women with Excessive Hair Dermatologic clinics · 2012
    3. Specific Dermatologic Features of Polycystic Ovary Syndrome and Its Association with Biochemical Markers of Metabolic Syndrome and Hyperandrogenism Acta Obstetricia et Gynecologica Scandinavica · 2010
    4. Spironolactone Versus Placebo or in Combination with Steroids for Hirsutism and/or Acne Cochrane library · 2009
    5. The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report Fertility and Sterility · 2008
    6. Medical Treatment of Hirsutism Dermatologic therapy · 2008
    7. Insulin Sensitizers for the Treatment of Hirsutism: A Systematic Review and Meta-Analyses of Randomized Controlled Trials The Journal of Clinical Endocrinology & Metabolism · 2008
    8. Evaluation and Treatment of Hirsutism in Premenopausal Women: An Endocrine Society Clinical Practice Guideline The Journal of Clinical Endocrinology & Metabolism · 2008
    9. Dermatologic Manifestations of Polycystic Ovary Syndrome American Journal of Clinical Dermatology · 2007
    10. Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline The Journal of Clinical Endocrinology and Metabolism · 2006
    11. Randomized, Double-Blind Clinical Evaluation of the Efficacy and Safety of Topical Eflornithine HCl 13.9% Cream in the Treatment of Women with Facial Hair International Journal of Dermatology · 2006
    12. Diagnosis and Management of the Dermatologic Manifestations of Polycystic Ovary Syndrome Dermatologic therapy · 2006
    13. Relative Prevalence of Different Androgen Excess Disorders in 950 Women Referred Because of Clinical Hyperandrogenism The Journal of Clinical Endocrinology and Metabolism · 2006
    14. Effective Treatment of Female Androgenic Alopecia with Dutasteride PubMed · 2005
    15. Treatment of Female Pattern Hair Loss With Oral Antiandrogens British Journal of Dermatology · 2005
    16. Finasteride Versus Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism International journal of gynaecology and obstetrics · 2004
    17. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    18. Androgen Excess in Women: Experience with Over 1000 Consecutive Patients The Journal of Clinical Endocrinology and Metabolism · 2004
    19. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    20. Prevalence of Polycystic Ovaries in Women with Androgenic Alopecia European journal of endocrinology · 2003
    21. Cyproterone Acetate for Hirsutism Cochrane library · 2003
    22. Metformin or Antiandrogen in the Treatment of Hirsutism in Polycystic Ovary Syndrome ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2003
    23. Pharmacologic Treatment of Polycystic Ovary Syndrome Seminars in reproductive medicine · 2003
    24. Finasteride for Female Androgenetic Alopecia British Journal of Dermatology · 2002
    25. The Effect of Metformin on Hirsutism in Polycystic Ovary Syndrome European journal of endocrinology · 2002
    26. Comparison of Diane 35 and Diane 35 Plus Finasteride in the Treatment of Hirsutism Fertility and Sterility · 2001
    27. Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2000
    28. Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females ˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism · 2000
    29. Comparison of Finasteride Versus Flutamide in the Treatment of Hirsutism European journal of endocrinology · 1999
    30. Comparison of Flutamide and Spironolactone in the Treatment of Hirsutism: A Randomized Controlled Trial Fertility and Sterility · 1994
    31. Androgens Affect the Activity of Human Sebocytes in Culture Depending on the Localization of the Sebaceous Glands, and Their Effect Is Antagonized by Spironolactone Skin Pharmacology and Physiology · 1994
    32. The Effect of Cyproterone Acetate on Hair Roots and Hair Shaft Diameter in Androgenetic Alopecia in Females Springer eBooks · 1989
    33. Spironolactone in Combination Drug Therapy for Unresponsive Hirsutism Fertility and sterility · 1985
    34. Treatment of Hirsutism With Spironolactone JAMA · 1982

    Related research 12

    1. Cutaneous Manifestations of Polycystic Ovary Syndrome Current Opinion in Endocrine and Metabolic Research · 2020
    2. Clinico-Pathological Correlation in Indian Women Presenting with Cutaneous Features of Hyperandrogenism: A Cross-Sectional Study Medical journal of Dr. D.Y. Patil Vidyapeeth · 2020
    3. Cutaneous Manifestations of Polycystic Ovary Syndrome: A Cross-Sectional Clinical Study Indian Dermatology Online Journal · 2017
    4. Polycystic Ovary Syndrome in Childhood: Diagnostic and Therapeutic Challenges NEJM Journal Watch · 2015
    5. Female Hyperandrogenism Presse Medicale · 2013
    6. Managing the PCOS-Related Symptoms of Hirsutism, Acne, and Hair Loss Springer eBooks · 2013
    7. Non-Polycystic Ovary Syndrome–Related Endocrine Disorders Associated with Hirsutism European Journal of Clinical Investigation · 2011
    8. The Dermatologic Manifestation of Hyperandrogenism: A Retrospective Chart Review Journal of The American Academy of Dermatology · 2011
    9. Polycystic Ovary Syndrome and Acne Skin therapy letter · 2011
    10. The Clinical Evaluation of Hirsutism Dermatologic therapy · 2008
    11. Dermatology of Androgen-Related Disorders Clinics in Dermatology · 2006
    12. Therapeutic Effect of Spironolactone in Hyperandrogenism Syndrome Проблемы Эндокринологии · 1993