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    GlossaryGonadotropin-Releasing Hormone Agonists (GnRH agonist)

    medications that initially boost, then suppress, sex hormone production

    Gonadotropin-Releasing Hormone Agonists (GnRH agonists) are medications that mimic the natural hormone GnRH, which regulates the release of other hormones like luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Initially, they increase the production of these hormones, but with continuous use, they suppress their release, leading to reduced levels of sex hormones such as testosterone and estrogen. This makes them useful in treating hormone-sensitive conditions like prostate cancer, endometriosis, and certain types of breast cancer.

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      research Management of Hirsutism

      55 citations, March 2000 in “American journal of clinical dermatology”
      Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
      Hormonal Therapies for Acne

      research Hormonal Therapies for Acne

      26 citations, October 2016 in “Clinics in Dermatology”
      Hormonal treatments can improve acne, but they come with potential side effects and risks.
      Hormone Therapy in Acne

      research Hormone Therapy in Acne

      24 citations, January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”
      Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
      Anti-Androgens for the Treatment of Hirsutism

      research Anti-Androgens for the Treatment of Hirsutism

      24 citations, March 2002 in “Expert opinion on investigational drugs”
      Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

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