Nutraceutical Intervention of Seeds in the Treatment of Polycystic Ovarian Syndrome: A Systematic Review

This systematic review investigates the efficacy of seed cycling, an alternative medicine approach, in treating Polycystic Ovary Syndrome (PCOS), a condition characterized by cyst formation in the ovaries, irregular menstrual cycles, abnormal hair growth, acne, mood swings, and hormonal imbalances. The review focuses on the use of flax, sesame, pumpkin, and sunflower seeds at different stages of the menstrual cycle. Flaxseeds, with their lignans, omega-3 fatty acids, and fiber, are noted to help alleviate PCOS symptoms. Sesame and sunflower seeds are highlighted for their fatty acids and lignans, which may assist in hormonal balance. Additionally, a diet rich in fiber is mentioned as beneficial for weight loss, improving cholesterol levels, and reducing insulin resistance, which can lead to type 2 diabetes mellitus and its complications. The review also acknowledges the potential of Ayurvedic herbal medicine in managing pre-menstrual symptoms, hormonal fluctuations, and associated comorbidities of PCOS.