10 citations
,
September 2022 in “Advanced Healthcare Materials” This review discusses recent advancements and ongoing challenges in engineering human skin with appendages using scaffold-free and scaffold-based bioengineering approaches, but it reports no new clinical results.
March 2026 in “IP Indian Journal of Conservative and Endodontics” This review discusses the use of platelet-rich plasma in regenerative dentistry, highlighting its biological principles, clinical applications, and the challenges encountered in PRP-based strategies for oral tissue engineering, but reports no new results.
421 citations
,
January 2015 in “Chemical Society Reviews” This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.
1 citations
,
January 2019 in “Elsevier eBooks” This review discusses scaffold materials and properties used in epidermal tissue engineering to promote skin regeneration and reports no new research findings.
1 citations
,
June 2025 in “Journal of Materials Science Materials in Medicine” This study reports that multifunctional electrospun scaffolds containing silver vanadate, hydroxyapatite, and graphene oxide significantly improved wound healing in a rat model, promoting rapid re-epithelialization, enhanced mechanical properties, and strong antibacterial activity, making them promising candidates for advanced wound care applications.
8 citations
,
May 2024 in “ACS Applied Materials & Interfaces” This study found that incorporating PCL-based nanoscaffolds into liver spheroids enhances their viability and liver-specific biofunctionality, suggesting these scaffolds improve the model's potential for preclinical drug screening by increasing sensitivity to acetaminophen toxicity compared to traditional methods.
114 citations
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November 2022 in “Biomedicine & Pharmacotherapy” This review discusses current wound management strategies and examines electrospun nanofibers with biological macromolecules for their potential in tissue engineering and drug delivery, but reports no new clinical results.
2 citations
,
November 2023 in “International Journal for Research in Applied Science and Engineering Technology” This review explores various tissue regeneration technologies, highlighting how skin substitutes have significantly improved healing success rates for burn injuries, and examines cell-based therapies aimed at reducing scar formation and improving burn management.
40 citations
,
January 2009 in “Skin Pharmacology and Physiology” This review discusses the potential use of cultured primary fetal cells from a single organ donation to produce therapeutic products, emphasizing the need for process consistency and safety verification, but reports no clinical results.
7 citations
,
February 2018 in “InTech eBooks” This article reviews how biomaterials and stem cells could advance regenerative medicine but does not report new results, emphasizing the potential of combining novel biomaterials with stem cells for effective therapies.
April 2025 in “BioNanoScience” New methods using biomaterials, stem cells, and nanoparticles show promise for improving hair growth and treating hair loss.
8 citations
,
May 2023 in “Gels” This review discusses the advantages and progress of chitosan hydrogels in vascular regeneration for tissue engineering scaffolds, highlighting modifications to enhance their application and exploring future prospects.
August 2025 in “Journal of Polymer Science” This review reports that combining adipose-derived stem cells with decellularized extracellular matrix enhances tissue repair by improving scaffold biological activity and promoting angiogenesis, integration, and functional regeneration across various tissues, while addressing challenges in traditional transplantation methods.
1 citations
,
March 2024 in “Nanomaterials” This review article summarizes recent advancements in biomimetic scaffolds, highlighting their promise in tissue engineering and personalized medicine, particularly for skin and musculoskeletal system regeneration, while emphasizing the need for more extensive research to ensure their safety for human use.
78 citations
,
February 2024 in “ACS Omega” This study developed a bilayer material combining poly(vinyl alcohol) and bacterial cellulose with a gelatin-poly(vinyl alcohol) hydrogel, showing strong potential as a wound dressing due to its good antibacterial properties, cell viability, and sustained drug release.
1 citations
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July 2025 in “The Open Dermatology Journal” This study explores the transformative role of tissue engineering in cosmetics, highlighting innovations like lab-grown skin and personalized grafts that enhance product efficacy, offer ethical alternatives to animal testing, and address aesthetic issues such as scarring and aging.
29 citations
,
April 2020 in “Biomolecules” The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.
6 citations
,
July 2025 in “Advanced Materials” This review discusses cell membrane-coated scaffolds in tissue engineering, emphasizing their potential to enhance therapeutic outcomes in regenerative medicine and reporting no new experimental results.
294 citations
,
January 2016 in “Stem Cells International” This review discusses the characteristics, biomaterials, and tissue engineering methods for adipose-derived stem cells in a 3D environment, highlighting their potential in regenerative medicine without presenting new clinical results.
47 citations
,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” This article reviews the generation of complex integument patterns through genetic, chemical, and environmental influences, with applications in tissue engineering, but reports no new experimental results.
192 citations
,
January 2018 in “Burns & Trauma” This review discusses the advancements in biologic skin substitutes for wound treatment and their potential in enhancing cutaneous regeneration but reports no new clinical results.
12 citations
,
September 2023 in “Polymers” This study reported that a newly developed hydrogel composed of recombinant type I collagen and chitosan, incorporating a metal–polyphenol structure, demonstrated strong mechanical and healing properties, effectively promoting wound healing in a full-thickness skin defect model.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
162 citations
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July 2011 in “Biomacromolecules” This study found that chitosan nanofibrillar scaffolds accelerated skin wound healing in mice by enhancing cell adhesion, proliferation, and regeneration of epidermis and dermis compared to other forms.
21 citations
,
November 2020 in “Chemical Engineering Journal” In this study, an injectable hydrogel incorporating antibacterial agents was shown to effectively heal wounds and promote hair follicle and capillary regeneration, offering a promising approach for skin tissue engineering.
7 citations
,
January 2019 in “Methods in molecular biology” This chapter describes methods for creating engineered skin substitutes with chimeric hair follicles using human and murine cell grafts in immunodeficient mice, but reports no clinical outcomes.
70 citations
,
August 2020 in “Nanomaterials” This review discusses the development of electrospun nanofibrous scaffolds for promoting angiogenesis in tissue engineering but notes that their clinical application beyond bone and skin repair is still limited.
17 citations
,
October 2023 in “Polymers” This review highlights advancements in electrospun nanofibers, focusing on their potential applications in biomedical technologies, chemical and biological sensing, and energy harvesting within IoT devices.
7 citations
,
May 2023 in “Macromolecular Bioscience” This review discusses recent advancements in using macromolecules for hair loss treatment, highlighting microneedle and nanoparticle delivery systems, tissue-engineered scaffolds for hair follicle regeneration, and artificial skin platforms as drug screening methods.
41 citations
,
September 2017 in “Advanced Healthcare Materials” This study found that the DexIEME hydrogel promotes complete skin regeneration and scar attenuation in murine and porcine models, suggesting potential for treating deep dermal injuries.