research Regenerative Medicine Applications in Dermatology and Aesthetics
Regenerative medicine shows promise for improving hair and skin but needs more research for standard use.
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research Inflammation in Androgenetic Alopecia and Hair Loss: Linking Neurosciences, Endocrinology, and Dermatology
Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.
research Clinical And Preclinical Approach In AGA Treatment: A Review Of Current And New Therapies In The Regenerative Field
New regenerative therapies show promise for treating hair loss.
research Retinoic Acid Drives Hair Follicle Stem Cell Activation via Wnt/Beta-Catenin Signalling in Androgenetic Alopecia
Retinoic acid helps activate hair growth in people with common hair loss by working on a specific cell growth pathway.
research Beta-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress
NMN could potentially treat hair loss by reducing oxidative stress and improving cell health.
research Minoxidil May Suppress Androgen Receptor-Related Functions
Minoxidil can reduce functions related to androgen receptors.
research Single-Cell Sequencing Reveals Differential Cell Types in Skin Tissues of Liaoning Cashmere Goats and Key Genes Potentially Related to the Fineness of Cashmere Fiber
Certain genes are linked to the quality of cashmere in goats.
research Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth? A Review Comparing Their Therapeutic Efficacies, Phytochemical Components, and Modulatory Targets
Plant extracts can help prevent hair loss and promote hair growth.
research Justicia Procumbens Prevents Hair Loss in Androgenic Alopecia Mice
Justicia procumbens extract may help prevent hair loss and improve hair thickness and shine in a type of hair loss condition.
research Extracellular Vesicles: Emerging Therapeutics in Cutaneous Lesions
Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.
research K15 And Id3 Expression In Intact And Regenerating Adult Vibrissae Rodent Hair Follicles
K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.
research Gab1 and MAPK Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
research The Synergistic Effect of Phototherapy and Active Substances on Hair Growth
Combining light therapy with certain substances improves hair growth in people with hair loss.
research Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression
The study investigated the role of Patched1 (Ptch1) in cell cycle progression and its function as a gatekeeper in preventing tumorigenesis, particularly in skin tumors resembling human basal cell carcinoma (BCC). Researchers found that loss of Ptch1 in mouse models led to rapid skin tumor formation, increased nuclear accumulation of cyclin D1 and B1, and enhanced cell proliferation, indicating Ptch1's role as a tumor suppressor. The study highlighted that Ptch1 loss predisposed cells to a tumorigenic fate by facilitating cell cycle progression, rather than through Wnt signaling. The research suggested that targeting the Hedgehog pathway, which involves Ptch1, could be a potential therapeutic strategy for cancer treatment, as inhibiting this pathway induced tumor regression in Ptch1-deficient mice.
research Animal and In Vitro Models for the Study of Hair Follicles
The document reviewed various in vitro and in vivo models used to study hair follicles, focusing on their role in understanding hair growth and disorders like androgenetic alopecia and alopecia areata. It discussed the use of genetically modified animals and cell cultures, such as dermal papilla cells, to explore the biological and biochemical mechanisms of hair follicles. These models provided insights into the effects of androgens and growth factors on hair growth, highlighting the importance of synthesizing information from different models due to the unique characteristics of human hair growth. The research aimed to facilitate a better understanding of hair follicle function and aid in developing novel treatments for hair disorders.
research MHC Class I-Like MILL Molecules Are β2-Microglobulin-Associated, GPI-Anchored Glycoproteins That Do Not Require TAP for Cell Surface Expression
MILL molecules are unique immune proteins in mice that don't need TAP to appear on cell surfaces.
research Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation
Fat under the skin releases HGF which helps hair grow and gain color.
research Increasing GSH-Px Activity and Activating Wnt Pathway Promote Fine Wool Growth in FGF5-Edited Sheep
Editing the FGF5 gene in sheep increases fine wool growth.
research DNA Dioxygenases Tet1/2/3 Control Cell Differentiation in Hair Follicle Keratinocytes via Modulating BMP Signaling Pathway
Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.
research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial
Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
research Expression of Potential Dermal Progenitor Cell Markers in the Tumor and Stroma of Skin Adnexal Malignant and Benign Tumors
Markers CRABP1, Nestin, and Ephrin B2 are present in skin cancer environments and may influence their development.
research The Proximal Promoter of the Human Transglutaminase 3 Gene
The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
research Organization and Expression of Hair Follicle Genes
Hair growth is controlled by specific gene clusters and proteins, and cysteine affects hair gene expression in sheep.
research Hair Biology and Care Product Ingredients from Marine Organisms
Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.
research Evaluation of Hair Regrowth by Cyclosporine and Minoxidil Using C3H Mouse Model
Cyclosporine starts hair growth faster, while minoxidil makes it last longer.
research The Biology of Hair Growth
Hair growth is influenced by hormones and goes through different phases; androgens can both promote and inhibit hair growth depending on the body area.
research Procyanidin B-3, Isolated from Barley and Identified as a Hair-Growth Stimulant, Has the Potential to Counteract Inhibitory Regulation by TGF-β1
Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.
research Targeted Expression of SV40 T Antigen in the Hair Follicle of Transgenic Mice Produces an Aberrant Hair Phenotype
SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
research Brain-Derived Nerve Factor and Neurotrophins in Androgenetic Alopecia
Lower growth factors linked to balding in androgenetic alopecia.
research Co-Expression Pattern of VEGFR-2 With Indicators Related to Proliferation, Apoptosis, and Differentiation of Anagen Hair Follicles
VEGFR-2 activation is likely involved in hair follicle growth, survival, and development.