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This study found that isotretinoin decreases mTORC1 signaling in acne skin, suggesting that mTOR inhibitors may have potential therapeutic benefits for acne patients.

This study isolated highly pure oleanolic and maslinic acids from olive milling residues, exploring their chemical reactions, including the formation of finasteride precursors.

This study found that Synechococcus elongatus PCC 11801 responded to increased CO2 concentrations by enhancing photosynthesis and carbon fixation while reducing other metabolic pathways, suggesting its potential for efficient CO2 capture.

This study suggests that RORα, RORβ, and RORγ mRNA expression in cashmere goat skin is related to different stages of hair follicle development, indicating a possible role in cycled cashmere growth.

This study identified key proteins, FKBP10 and FBN2, that promote the growth cycle of secondary hair follicles in cashmere goats, with higher expression in the anagen phase, offering insights into mechanisms potentially enhancing cashmere yield and quality.

In this study, researchers characterized a dehydroepiandrosterone hydroxylating enzyme system in hair follicles similar to the liver monooxygenase system, noting its inhibition by carbon monoxide and its dependence on NADPH.

This study identifies novel subpopulations of human epidermal melanocytes and specific transcriptional programs that differ from model organisms, providing insights into melanoma dedifferentiation.

This study provided the first proteome dataset for alopecia areata, revealing novel pathways in the disease mechanisms that may lead to new therapeutic targets.

This study on the sheepgenomics program reported significant progress in identifying genes that can be manipulated to enhance wool production and quality in sheep.

This study found that Asparagus racemosus root extract significantly reduced facial sebum production and pore size in male volunteers, suggesting potential application as an anti-sebum ingredient in cosmetics.

In this study, inducible whole-body Acly-knockout mice revealed that ACLY is essential for skin homeostasis, as its deficiency led to increased sebum production and skin abnormalities, indicating a vital role for cytosolic acetyl-CoA synthesis in preserving skin barrier integrity and systemic lipid regulation.

This article reviews the historical discovery and validation of isocholesterol, confirming its identity as a distinct sterol but reports no new research findings.

This study found that TLR3 activation in human keratinocytes enhances exosome biosynthesis and expression of hair follicle stem cell markers, suggesting a potential mechanism for tissue regeneration.

The researchers reported that epitestosterone treatment reduced eicosanoid levels generated by cyclooxygenases and lipoxygenases in rabbit liver samples with carrageenan-induced inflammation.

This study identified that the enzyme CYP2B12 is skin-specific and likely plays a role in the metabolism of arachidonic acid, a key component in lipid signaling within sebaceous glands.

This paper highlights the growing interest in exosomes for their therapeutic and diagnostic potential in cosmetic dermatology, noting their roles in skin rejuvenation, postprocedural care, and antiaging treatments.

In this study, researchers used proteomic and metabolomic analyses to explore hair follicle development in embryonic cashmere goats, identifying significant roles for the oxytocin signalling pathway and associated networks in this process.

The researchers reported that disrupting ATRA signaling by deleting RDHE genes in the hair follicle led to altered hair follicle cycles, composition, and gene expression, indicating RDHEs' role in hair follicle signaling coordination.

This study sequenced and analyzed the goat skin transcriptome, revealing genes involved in signal transduction and cell communication that are differentially expressed during hair growth phases, providing insights for Cashmere goat breeding.

In this study, researchers identified that upon tissue injury in a mouse model, epidermal cells at the wound edge convert to an embryonic-like state with SOX11 and SOX4 playing a central role in modulating epidermal development and cell migration genes.

This study reported a new method enabling the observation of the full leg regeneration process in the crustacean *Parhyale hawaiensis* over 10 days, capturing cellular resolution while minimizing photodamage, through innovative imaging techniques and computer-assisted cell tracking.

Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.

The study characterized the transcriptional changes in porcine SKP cells transitioning to fibroblast-like cells, indicating potential roles for specific signaling pathways in this cell fate transition.

This review synthesizes current advances in transcriptomics and RNA regulatory networks, alongside stem cell-derived skin organoid research, to propose a conceptual framework for understanding and potentially guiding regenerative skin repair, without claiming clinical readiness.

In this study, researchers used single-cell RNA sequencing to identify cell types and molecular differences in subcutaneous adipose tissue from various anatomical sites, suggesting that certain subpopulations of human adipose stem cells might improve the treatment of chronic refractory wounds.

This study suggests that incorporating matrisomal components into biomaterials could enhance skin wound healing in mammals that do not naturally regenerate tissues like the axolotl and Acomys.

This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.