NRF2 Coordinates Ferroptosis and Disulfidptosis in Dermal Papilla Cells via Redox Metabolic Reprogramming in Androgenetic Alopecia

    May 2026 in “ Free Radical Biology and Medicine ”
    Xiaowen Mao, W Zhou, Weiyi An … Hongyun Zhao
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    Research cited in this study 8

    1. Arginine Metabolic Disruption Impairs Hair Regeneration via ROS-Mediated Inactivation of mTOR Signaling in Androgenetic Alopecia PubMed · 2025
    2. Retinoic Acid Drives Hair Follicle Stem Cell Activation via Wnt/Beta-Catenin Signalling in Androgenetic Alopecia JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology · 2024
    3. Androgenetic Alopecia: Therapy Update Drugs · 2023
    4. Cyanidin 3-O-Arabinoside Suppresses DHT-Induced Dermal Papilla Cell Senescence by Modulating p38-Dependent ER-Mitochondria Contacts Journal of Biomedical Science · 2022
    5. Assessment of Human Nuclear Factor Erythroid 2 Related Factor 2 (NRF2) in Androgenetic Alopecia in Egyptian Men QJM: An International Journal of Medicine · 2021
    6. Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond? BioEssays · 2017
    7. Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015
    8. Hair Loss in Women: Medical and Cosmetic Approaches to Increase Scalp Hair Fullness British Journal of Dermatology · 2011