Research on Expression of Retinoid-Related Orphan Receptor (ROR) in the Skin of Cashmere Goat

January 2010 in “ China Animal Husbandry & Veterinary Medicine ”

Jinquan Li

TLDR RORs may influence cashmere growth cycles.

The study investigated the expression of retinoid-related orphan receptors (RORα, RORβ, and RORγ) in the skin of Inner Mongolia cashmere goats to determine if melatonin's effects might involve nuclear receptors. mRNA was extracted and analyzed from different stages of hair follicle development. The results showed that RORα, RORβ, and RORγ mRNA were expressed during catagen (January), early anagen (May), and anagen (September) phases, but not during the telogen phase (March). This suggested that RORs might be related to the cyclical growth of cashmere.

View this study on en.cnki.com.cn →

Discuss this study in the Community →

Related Community Posts Join

6 / 122 results

community Has anybody tried retinol (not Retin A aka tretinoin) combined with minoxidil?

in Treatment 20 upvotes 2 years ago

The conversation is about someone who had success using retinol with minoxidil for hair growth, but experienced shedding with Retin A (tretinoin). They are asking if others have tried retinol with minoxidil and what their results were.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Minoxidil seems logistically impossible and impractical to use

in Minoxidil 136 upvotes 1 year ago

The post discusses concerns about the practicality of using Minoxidil foam for hair loss, including the frequency of application, preparation, coverage area, and drying time. Responses suggest that missing a dose isn't detrimental, it can be applied once a day, it works on all hair areas, and it doesn't need to be perfectly dry before application.

community Collagen/Vitamins/Supplements and skin-care routine while on Minoxidil?

in Minoxidil 29 upvotes 4 years ago

Minoxidil users discuss skin-care routines to counteract side effects like dark circles and dull skin. Recommendations include vitamin C, potassium, collagen, retinol, nizoral shampoo, and emu oil.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Min users : Who can name a specific product that offset the development of Min-related lines and wrinkles in your skin ? There are lots of vague 'try Retinol-A' or 'Zinc' or this or that, but has anyone actually gone and got some shit and had it halt wrinkling ?

in Question 6 upvotes 7 years ago

The conversation discusses treatments to counteract skin wrinkles caused by Minoxidil use. Suggestions include Retinol-A and Zinc, but users seek specific products that have effectively halted wrinkling.

Related Research

2 / 2 results

research Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-Catenin in Inner Mongolia Cashmere Goats

9 citations, July 2021 in “Frontiers in genetics”

Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.

research DHT and E2 Synthesis-Related Proteins and Receptors Expression in Male Yak Skin During Different Hair Follicle Stages

4 citations, August 2019 in “General and Comparative Endocrinology”

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.