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Non-immune dermal cells dominate, epidermal cells increase after day 9, and certain immune cells persist beyond inflammation in wound-induced hair follicle regeneration.

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

Hydrogel scaffolds can help wounds heal better and grow hair.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Aging slows wound healing due to weaker cells and immune response.

Understanding how Regulatory T Cells work could help create treatments for certain skin diseases and cancers.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The nail matrix has a reduced immune response, protecting it from autoimmunity.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Early exposure to germs may protect against autoimmune diseases, lack of sex increases alcohol preference in fruit flies, a potential baldness treatment could involve blocking a specific receptor, skin memory cells help prevent re-infection, high-fat diets can affect brain cells related to weight, and the link between social status, stress, and heart disease in primates is unclear.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Fat cells in the skin help start healing and form important repair cells after injury.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

Skinny fat cells help wounds heal faster by releasing fatty acids.

Radiation therapy damages skin structure and immune function, causing inflammation and potential hair loss.

ILC1-like cells may contribute to hair loss in alopecia areata.

ILC1-like cells may contribute to hair loss in alopecia areata and could be new treatment targets.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Different parts of the body have unique immune characteristics in their skin.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

New treatments targeting T-cell pathways are needed for better alopecia areata management.