Signaling in the Stem Cell Niche: Regulating Cell Fate, Function, and Plasticity

    August 2018 in “ Development ”
    Carlos Andrés Chacón‐Martínez, Janis Koester, Sara A. Wickström
    Studysummary This review discusses the dynamic, niche-driven regulation of stem cell states in tissue homeostasis and regeneration, focusing on epithelial stem cells in the mammalian skin, intestine, and lung, without providing new experimental results.
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    Research cited in this study 13

    1. Stem Cell Plasticity Enables Hair Regeneration Following Lgr5+ Cell Loss Nature Cell Biology · 2017
    2. Hair Follicle Stem Cell Cultures Reveal Self-Organizing Plasticity of Stem Cells and Their Progeny The EMBO Journal · 2016
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    8. Spatial Organization Within a Niche as a Determinant of Stem-Cell Fate Nature · 2013
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    10. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
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    13. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001