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GlossaryStromal Cells

connective tissue cells supporting organ structure and function

Stromal cells are a type of connective tissue cell found in various organs, including the skin, bone marrow, and fat. They provide structural support and secrete factors that help regulate the function and growth of nearby cells, including those involved in hair growth and repair. For professionals, stromal cells are crucial in tissue engineering and regenerative medicine due to their role in creating a supportive microenvironment for tissue regeneration.

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research States and Fates of Skin Fibroblasts Revealed Through Chromatin Accessibility

February 2022 in “Journal of Investigative Dermatology”

Newborn skin cells can change into wound-healing cells more easily than adult ones, which might explain why baby skin heals without scars. Understanding this could help treat chronic wounds and prevent scarring.

research Lef1 Expression in Fibroblasts Maintains Developmental Potential in Adult Skin to Regenerate Wounds

June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Lef1 helps adult skin cells maintain their ability to heal wounds and regenerate hair, but the study's methods and conclusions have been questioned.

research RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation

42 citations, December 2011 in “The journal of immunology/The Journal of immunology”

RANKL causes lymph nodes to grow by making certain cells multiply.

Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes

81 citations, September 2005 in “The American journal of pathology”

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

research Distinct Expression Profile of Stem Cell Markers, LGR5 and LGR6, in Basaloid Skin Tumors

9 citations, January 2017 in “Virchows Archiv”

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

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community This guy claims stem cells fixed his balding

in Is this regrowth? 301 upvotes 1 year ago

A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 864 upvotes 4 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 9 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.