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GlossaryStromal Cells

connective tissue cells supporting organ structure and function

Stromal cells are a type of connective tissue cell found in various organs, including the skin, bone marrow, and fat. They provide structural support and secrete factors that help regulate the function and growth of nearby cells, including those involved in hair growth and repair. For professionals, stromal cells are crucial in tissue engineering and regenerative medicine due to their role in creating a supportive microenvironment for tissue regeneration.

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research Distinct Expression Profile of Stem Cell Markers, LGR5 and LGR6, in Basaloid Skin Tumors

9 citations , January 2017 in “Virchows Archiv”

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

research Stromal Cells of the Human Postmenopausal Ovary Display a Distinctive Biochemical and Molecular Phenotype

June 2003 in “Obstetrical & Gynecological Survey”

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

Immunohistochemical Analysis of Estrogen and Progesterone Receptors in Endometrium and Peritoneal Endometriosis: A New Quantitative Method

research Immunohistochemical Analysis of Estrogen and Progesterone Receptors in Endometrium and Peritoneal Endometriosis: A New Quantitative Method

June 1995 in “International Journal of Gynecology & Obstetrics”

The new method showed that endometriotic tissue has lower estrogen receptor levels but similar progesterone levels compared to normal endometrium, with both following a similar cycle.

research Depletion of S100A4+ Stromal Cells Results in Abnormal Nipple Development and Nursing Failure

January 2026

Lack of certain cells causes abnormal nipple development and nursing failure.

research The Microanatomy of Human Skin in Aging

5 citations , April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.

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community This guy claims stem cells fixed his balding

in Is this regrowth? 327 upvotes 2 years ago

A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 7 upvotes 1 year ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Fresh off the press: Dutasteride may cause chronic infertility

in Research/Science 643 upvotes 11 months ago

Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.