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    Glossary Stromal Cells

    connective tissue cells supporting organ structure and function

    Stromal cells are a type of connective tissue cell found in various organs, including the skin, bone marrow, and fat. They provide structural support and secrete factors that help regulate the function and growth of nearby cells, including those involved in hair growth and repair. For professionals, stromal cells are crucial in tissue engineering and regenerative medicine due to their role in creating a supportive microenvironment for tissue regeneration.

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    1. Conditioned Medium from Human Mesenchymal Stromal Cells: Towards the Clinical Translation International Journal of Molecular Sciences · 2019 · 166 citations
    2. Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes ˜The œAmerican journal of pathology · 2005 · 81 citations
    3. LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway Stem cell research & therapy · 2016 · 53 citations
    4. Macrophage ferroportin is essential for stromal cell proliferation in wound healing Haematologica · 2018 · 45 citations
    5. RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation 2011 · 42 citations
    6. A randomized, controlled clinical trial of autologous stromal vascular fraction cells transplantation to promote mechanical stretch-induced skin regeneration Stem Cell Research & Therapy · 2021 · 19 citations
    7. γδ17 T cell-stromal networks modulate matrix composition and vascularity in foreign body response 2026 · 1 citations
    8. Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure 2026
    9. Supercharged Mechanical Stromal-Cell Transfer (MEST) Medical Times · 2023
    10. Stromal Cells of the Human Postmenopausal Ovary Display a Distinctive Biochemical and Molecular Phenotype Obstetrical & Gynecological Survey · 2003
    11. A systematic review of clinical evidence on the efficacy and safety of conditioned media, platelet-rich fibrin, stromal vascular fraction, extracellular vesicles, and stem cells in androgenetic alopecia Stem Cell Research & Therapy · 2026
    12. The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair Science · 2009 · 295 citations
    13. The Combination of Stromal Vascular Fraction Cells and Platelet-Rich Plasma Mediates the Inflammatory Process in Deep Dermal Burn Injury. PubMed · 2023 · 1 citations
    14. Inflammatory priming enhances mesenchymal stromal cell secretome potential as a clinical product for regenerative medicine approaches through secreted factors and EV-miRNAs: the example of joint disease Stem Cell Research & Therapy · 2020 · 118 citations
    15. Mesenchymal Stem Cells and Stromal Vascular Fraction for Hair Loss Facial Plastic Surgery Clinics of North America · 2018 · 13 citations
    16. Human Adipose-Derived Mesenchymal Stromal Cells Exhibit High HLA-DR Levels and Altered Cellular Characteristics under a Xeno-free and Serum-free Condition Stem Cell Reviews and Reports · 2021 · 12 citations
    17. Mesothelial Stem Cells and Stromal Vascular Fraction for Skin Rejuvenation Facial Plastic Surgery Clinics of North America · 2018 · 11 citations
    18. Mesenchymal stem/stromal cell therapy in atopic dermatitis and chronic urticaria: immunological and clinical viewpoints Stem Cell Research & Therapy · 2021 · 8 citations
    19. Towards a consensus potency assay for mesenchymal stromal cells: a matrix analysis of cell source, donor variability and inflammatory stimuli to refine surrogate markers of immunomodulation Cytotherapy · 2019 · 3 citations
    20. Immortalized human hair follicle-derived mesenchymal-like stromal cells for the long-term production of scalable Immunomodulatory and regenerative secretome Stem Cell Research & Therapy · 2025 · 1 citations
    21. Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro Human Cell · 2026
    22. Morphometric prediction of mesenchymal stromal cell-like immunosuppressive capacity of human hair follicle dermal sheath cup cells: an implication for regenerative medicine in hair loss diseases Stem Cell Research & Therapy · 2025
    23. Dual deficiency of melatonin and dihydrotestosterone promotes stromal cell damage and mediates prostatitis via the cGAS-STING pathway in sleep-deprived mice Cell communication and signaling · 2024
    24. Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning Frontiers in Immunology · 2018 · 320 citations
    25. Challenges and Strategies for Improving the Regenerative Effects of Mesenchymal Stromal Cell-Based Therapies International Journal of Molecular Sciences · 2017 · 269 citations
    26. Single-cell RNA-seq highlights heterogeneity in human primary Wharton’s jelly mesenchymal stem/stromal cells cultured in vitro Stem Cell Research & Therapy · 2020 · 116 citations
    27. Mesenchymal stromal cells in hepatic fibrosis/cirrhosis: from pathogenesis to treatment Cellular and Molecular Immunology · 2023 · 99 citations
    28. Immunomodulatory properties of mesenchymal stromal/stem cells: The link with metabolism Journal of Advanced Research · 2022 · 83 citations
    29. Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells Cell Death and Disease · 2020 · 52 citations
    30. In vitro characterization of human hair follicle dermal sheath mesenchymal stromal cells and their potential in enhancing diabetic wound healing Cytotherapy · 2015 · 52 citations