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    Glossary Receptors

    specialized proteins that bind specific molecules to trigger cellular responses

    Receptors are specialized protein molecules found on the surface of cells or within cells that bind to specific substances, such as hormones, neurotransmitters, or drugs. When these substances attach to the receptors, they trigger a response within the cell, influencing various physiological processes. For example, in the context of hair biology, androgen receptors on hair follicle cells can bind to hormones like testosterone, affecting hair growth and potentially contributing to conditions like androgenetic alopecia (pattern baldness).

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    1. Receptor types in cat hairy skin supplied by myelinated fibers. Journal of neurophysiology · 1968 · 307 citations
    2. Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster. Proceedings of the National Academy of Sciences · 1984 · 164 citations
    3. Androgen receptor–mediated inhibition of cutaneous wound healing 2002 · 108 citations
    4. Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit Proceedings of the National Academy of Sciences of the United States of America · 2011 · 60 citations
    5. Down-regulation of Melanocortin Receptor Signaling Mediated by the Amino Terminus of Agouti Protein in XenopusMelanophores Journal of Biological Chemistry · 1999 · 43 citations
    6. Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization Structure · 2017 · 24 citations
    7. Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System Journal of Investigative Dermatology · 2000 · 16 citations
    8. Activation of extrasynaptic δ-GABAA receptors globally or within the posterior-VTA has estrous-dependent effects on consumption of alcohol and estrous-independent effects on locomotion Hormones and behavior · 2017 · 14 citations
    9. Epidermal expression of receptor for advanced glycation end products (RAGE) is related to inflammation and apoptosis in human skin Experimental Dermatology · 2015 · 10 citations
    10. Receptor tyrosine kinase Kit action in skin melanocytes: is it exclusively cell autonomous? Experimental Dermatology · 2015 · 1 citations
    11. The Role of the Vitamin D Receptor in the Epidermal Stem Cell Response to Wounding Receptors · 2024
    12. EXPRESSION CHARACTERISTICS OF bFGF, EGF, TGF-β ISOFORMS AND THEIR RECEPTORS IN SKIN FROM FETUS AND ADULT Jiefangjun yixue zazhi · 2003
    13. Receptors in trichology: Hot spots for hair regeneration International journal of trichology · 2013
    14. 078 The transmembrane protein LRIG1 regulates receptor tyrosine kinases in skin development and homeostasis Journal of Investigative Dermatology · 2017
    15. Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction Trends in Cell Biology · 2014 · 119 citations
    16. A Receptor-Like Kinase Mediates Ammonium Homeostasis and Is Important for the Polar Growth of Root Hairs in<i>Arabidopsis</i> ˜The œPlant cell · 2014 · 107 citations
    17. A Mutation of the Androgen Receptor Associated with Partial Androgen Resistance, Familial Gynecomastia, and Fertility* The Journal of Clinical Endocrinology & Metabolism · 1988 · 67 citations
    18. The investigation of selective sphingosine-1 phosphate receptor 1&4 modulator to treat alopecia areata mouse model 2881 The Journal of Immunology · 2025
    19. Feronia: A Malectin-Like Domain-Containing Receptor Kinase in Arabidopsis Thalina Scholarworks (University of Massachusetts Amherst) · 2021
    20. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997 · 416 citations
    21. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    22. Polymorphism of the Androgen Receptor Gene is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001 · 299 citations
    23. Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6 Journal of Biological Chemistry · 2009 · 253 citations
    24. Balding hair follicle dermal papilla cells contain higher levels of androgen receptors than those from non-balding scalp Journal of Endocrinology · 1998 · 227 citations
    25. Eph Receptors and Ephrins: Therapeutic Opportunities Annual Review of Pharmacology and Toxicology · 2014 · 222 citations
    26. The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors Drug Metabolism Reviews · 2006 · 219 citations
    27. Androgen receptor–mediated inhibition of cutaneous wound healing 2002 · 207 citations
    28. Androgen Receptor Antagonists (Antiandrogens) Structure-Activity Relationships Current Medicinal Chemistry · 2000 · 204 citations
    29. Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice Journal of Pharmacology and Experimental Therapeutics · 2004 · 180 citations
    30. The <i>hairless</i> gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor Genes & Development · 2001 · 178 citations