Respiratory Regulation by Steroids in Newborn Rats: A Sex-Specific Balance Between Allopregnanolone and Progesterone Receptors

    November 2017 in “ Experimental physiology ”
    Vincent Joseph, NagaPraveena Uppari, Hayet Kouchi … Aïda Bairam
    Studysummary This study found that in newborn rats, progesterone's effects on apnoea frequency are influenced by a sex-specific balance between its metabolite allopregnanolone and progesterone receptors.
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    Research cited in this study 2

    1. Inhibitory Respiratory Responses to Progesterone and Allopregnanolone in Newborn Rats Chronically Treated with Caffeine The Journal of Physiology · 2015
    2. Anesthetic Effects of Progesterone Are Undiminished in Progesterone Receptor Knockout Mice Brain Research · 2005

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