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GlossaryToll-like receptors

proteins on immune cells that detect pathogens and trigger responses

Toll-like receptors (TLRs) are proteins found on the surface of certain cells that play a crucial role in the immune system by recognizing and responding to pathogens like bacteria and viruses. They act as sentinels, detecting foreign molecules and triggering an immune response to help protect the body from infections.

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research Altered expression of intracellular Toll-like receptors in peripheral blood mononuclear cells from patients with alopecia areata

12 citations , June 2016 in “BBA clinical”

Increased Toll-like receptors in blood cells may contribute to alopecia areata and could be a target for new treatments.

research Toll-Like Receptor Function in Acute Wounds

65 citations , October 2017 in “Advances in wound care”

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

1425 Deregulation of toll like receptor signaling and association with caveolin-1 in lichen planopilaris reveals a novel mechanism in pathogenesis of scarring alopecia

research 1425 Deregulation of toll like receptor signaling and association with caveolin-1 in lichen planopilaris reveals a novel mechanism in pathogenesis of scarring alopecia

May 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study suggests that changes in immune system receptors and their interaction with a cell component may be important in the development of a type of hair loss condition.

research Essential Role of STAT3 Signaling in Hair Follicle Homeostasis

6 citations , November 2021 in “Frontiers in immunology”

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

research Highlights from the 68th Annual Meeting of the Society of Investigative Dermatology

September 2007 in “Journal of Investigative Dermatology”

The meeting discussed vitamin D3's role in fighting tuberculosis, potential treatments for skin conditions like psoriasis, and hair follicle regeneration as a possible solution for hair loss.

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community It’s crazy how it’s 2018 and the only hair loss treatments we have feature undesirable side effects and/or aren’t even effective for many people.

136 upvotes 6 years ago

Hair loss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hair loss treatments despite decades of research.

community Hairloss is mentally exhausting

in Chat 24 upvotes 3 years ago

The conversation is about the mental toll of hair loss and seeking alternatives to finasteride. Suggestions include using minoxidil, considering pumpkin seed oil, and possibly seeking counseling for body dysmorphic disorder.

community Why only the top of the head?!

in Chat 1 year ago

Why the top of the head is affected by hair loss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.

community Will my liver get destroyed long term on this stack ??

in Chat 15 upvotes 6 months ago

A user is considering a long-term hair loss treatment stack including Dutasteride, Finasteride, and oral Minoxidil, and is concerned about potential liver damage. Some responses suggest the stack is excessive, while others believe it's not harmful to the liver, but recommend regular blood work to monitor health.

community 5 Months Hair Transplant Progress / 3500 Grafts

in Transplants 1663 upvotes 8 months ago

A user shared their positive experience with a hair transplant of 3500 grafts, showing significant improvement in appearance after 5 months. They underwent the procedure at Heva Clinic in Istanbul for $2,300 USD, which included aftercare, and attributed their hair loss to both genetics and traction alopecia from tight hairstyles.

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