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GlossaryToll-like receptor 3

detects viral RNA to trigger immune responses

Toll-like receptor 3 (TLR3) is a protein that plays a crucial role in the immune system by recognizing and responding to viral infections. It detects double-stranded RNA, a molecular pattern associated with many viruses, and triggers an immune response to help fight off the infection.

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research Toll-like Receptor 3 Agonist, Polyinosinic-polycytidylic Acid, Upregulates Carbonic Anhydrase II in Human Keratinocytes

9 citations , January 2018 in “Acta dermato-venereologica”

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling

research A Population of Radio-Resistant Macrophages in the Deep Myenteric Plexus Contributes to Postoperative Ileus Via Toll-Like Receptor 3 Signaling

6 citations , January 2021 in “Frontiers in Immunology”

Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.

research Toll-Like Receptor Function in Acute Wounds

65 citations , October 2017 in “Advances in wound care”

Toll-like receptors are important for wound healing, but can slow it down in diabetic wounds.

research Toll-like receptor 4 (TLR4): new insight immune and aging

15 citations , November 2023 in “Immunity & ageing”

TLR4 is important in aging-related diseases and could be a new treatment target.

Hypothesis: Wound‐induced <scp>TLR</scp>3 activation stimulates endogenous retinoic acid synthesis and signalling during regeneration

research Hypothesis: Wound‐induced TLR3 activation stimulates endogenous retinoic acid synthesis and signalling during regeneration

5 citations , April 2019 in “Experimental dermatology”

Activating TLR3 may help produce retinoic acid, important for tissue regeneration.

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community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 2 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

community Hairloss is mentally exhausting

in Chat 24 upvotes 3 years ago

The conversation is about the mental toll of hair loss and seeking alternatives to finasteride. Suggestions include using minoxidil, considering pumpkin seed oil, and possibly seeking counseling for body dysmorphic disorder.

community C’est terrible - at my wits end

in Female 445 upvotes 9 months ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Testosterone is 1600, would taking low dose anti-androgens be a viable treatment option for people who’s T spikes on DHT-blockers?

in Treatment 46 upvotes 11 months ago

The post and conversation are about the user's high testosterone levels and their worsening hair loss despite trying various treatments. They are considering using low doses of anti-androgens to lower their testosterone levels as a potential solution.

community Why is nobody studying the difference between donor and balding hair?

in Chat 88 upvotes 2 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

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